Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SUT_RS06960 Genome accession   NZ_AP025331
Coordinates   1465355..1466011 (-) Length   218 a.a.
NCBI ID   WP_024532637.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1460355..1471011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS06940 (GUT183_13390) sodA 1460385..1460996 (-) 612 WP_155972515.1 superoxide dismutase SodA -
  SUT_RS06945 (GUT183_13400) holA 1461093..1462124 (-) 1032 WP_024532640.1 DNA polymerase III subunit delta -
  SUT_RS06950 (GUT183_13410) - 1462380..1462991 (-) 612 WP_237373046.1 hypothetical protein -
  SUT_RS06955 (GUT183_13420) comEC/celB 1463137..1465371 (-) 2235 WP_237373048.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SUT_RS06960 (GUT183_13430) comEA 1465355..1466011 (-) 657 WP_024532637.1 helix-hairpin-helix domain-containing protein Machinery gene
  SUT_RS06965 (GUT183_13440) - 1466096..1466839 (-) 744 WP_024532636.1 lysophospholipid acyltransferase family protein -
  SUT_RS06970 (GUT183_13450) - 1467030..1468475 (+) 1446 WP_237373049.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  SUT_RS06975 (GUT183_13460) - 1468835..1469623 (+) 789 WP_237373050.1 ABC transporter ATP-binding protein -
  SUT_RS06980 (GUT183_13470) - 1469633..1470562 (+) 930 WP_120171917.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23008.77 Da        Isoelectric Point: 4.4459

>NTDB_id=91143 SUT_RS06960 WP_024532637.1 1465355..1466011(-) (comEA) [Streptococcus ruminantium strain GUT-183]
MEKVIECIKEYKWQVGLPVIAVVVVASFLLFRQSAQPVDQTGLTKFSQTEQISSSQEVIEETSTEASEKNSKLVVDVKGA
VINPGLYTLETGARINDAIAAAGGFTSQADQKSINLAQKLTDETVVYVASQGENISVVPNSSTSSALSQEGNKSGLVNLN
TATVADLQTISGIGAKRAADIIAYREANGSFKSVDDLSNVSGIGDKTLESIRSYVTVG

Nucleotide


Download         Length: 657 bp        

>NTDB_id=91143 SUT_RS06960 WP_024532637.1 1465355..1466011(-) (comEA) [Streptococcus ruminantium strain GUT-183]
ATGGAAAAAGTTATTGAATGCATTAAAGAATACAAGTGGCAAGTTGGTCTGCCTGTGATAGCAGTAGTGGTGGTGGCGAG
TTTTCTTCTTTTTAGACAGTCAGCTCAGCCAGTTGACCAGACAGGATTGACCAAGTTTTCACAGACAGAACAAATCAGCT
CCAGTCAAGAAGTGATAGAAGAGACCTCAACAGAAGCTAGCGAGAAAAACAGCAAACTAGTGGTGGATGTCAAGGGTGCA
GTGATAAATCCCGGTCTTTACACCTTAGAGACTGGTGCCCGTATCAATGATGCCATTGCCGCAGCGGGCGGTTTCACTAG
TCAAGCAGATCAAAAATCTATCAATCTAGCGCAAAAGCTGACTGATGAAACAGTCGTCTATGTGGCTAGTCAGGGTGAGA
ATATTTCGGTAGTTCCCAATTCTTCAACTAGCTCAGCCCTGTCTCAAGAGGGAAATAAATCTGGTCTAGTTAATCTGAAT
ACAGCTACGGTGGCGGACTTACAGACCATTTCAGGCATCGGTGCTAAGCGAGCAGCGGATATTATTGCTTATCGTGAAGC
CAATGGTTCCTTCAAGTCGGTGGACGATCTCAGCAATGTTTCTGGCATTGGTGACAAGACCCTAGAAAGTATCCGATCCT
ATGTTACGGTTGGATAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(74-128)

Helix-hairpin-helix motif (HHH_3)

(155-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

47.807

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

46.637

100

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.119

100

0.463
  comEA/celA/cilE Streptococcus mitis SK321

44.495

100

0.445
  comEA Lactococcus lactis subsp. cremoris KW2

41.441

100

0.422
  comEA Bacillus subtilis subsp. subtilis str. 168

42.632

87.156

0.372

Multiple sequence alignment