Detailed information NTG0091142

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SUT_RS06955
• Genome accession: NZ_AP025331
• Coordinates: 1463137..1465371 (-)
• Length: 744 a.a.
• NCBI ID: WP_237373048.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-183
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1458137..1470371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUT_RS06930 (GUT183_13360)	-	1458842..1459006 (-)	165	WP_155969549.1	hypothetical protein	-
SUT_RS06935 (GUT183_13370)	-	1459133..1459756 (-)	624	WP_120171912.1	helix-turn-helix domain-containing protein	-
SUT_RS10375	-	1460002..1460192 (-)	191	Protein_1332	recombinase	-
SUT_RS06940 (GUT183_13390)	sodA	1460385..1460996 (-)	612	WP_155972515.1	superoxide dismutase SodA	-
SUT_RS06945 (GUT183_13400)	holA	1461093..1462124 (-)	1032	WP_024532640.1	DNA polymerase III subunit delta	-
SUT_RS06950 (GUT183_13410)	-	1462380..1462991 (-)	612	WP_237373046.1	hypothetical protein	-
SUT_RS06955 (GUT183_13420)	comEC/celB	1463137..1465371 (-)	2235	WP_237373048.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SUT_RS06960 (GUT183_13430)	comEA	1465355..1466011 (-)	657	WP_024532637.1	helix-hairpin-helix domain-containing protein	Machinery gene
SUT_RS06965 (GUT183_13440)	-	1466096..1466839 (-)	744	WP_024532636.1	lysophospholipid acyltransferase family protein	-
SUT_RS06970 (GUT183_13450)	-	1467030..1468475 (+)	1446	WP_237373049.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SUT_RS06975 (GUT183_13460)	-	1468835..1469623 (+)	789	WP_237373050.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84866.75 Da
• Isoelectric Point: 9.7221

>NTDB_id=91142 SUT_RS06955 WP_237373048.1 1463137..1465371(-) (comEC/celB) [Streptococcus ruminantium strain GUT-183]
MLRLDKLPCQPIHLAILAVVTYFTVHRFSMLTMSLLILLLIIFWRRQGKLTFFKMLPLLVLCGLFFGCQKLKWKQEEQAV
SKQVTAVEIVPDTININGDQLSFRARTDGQIYQGFYKLTSQKEQEYFQKLTALVQVEVKAETSLPSGQRNFNGFDYQAYL
KTQGIYRILTIATINKIVPIHSWNPMDWLSIWRRKALVFIKSNFPSPMSHYMTGLLFGELDSDFDQMSALYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDQLQVPFSLVYAGLTGFSVSVVRSLIQKILSNLGLRKLDNFAATLFICFLVQ
PRFLLTVGGVLTFTYAFLLTVFDFEDLKQIKKVVVESLSISLGILPILMTYFYAFQPLSILLTFFFSFVFDVLLLPSLSV
IFLLSPLVKITWVNSFFVLMEKMIIWVSDLGLRPLILGKPSDFILLVLLLGFFMLYDFHRQKKWLLGLSLLLTLLFFITK
HPLENEVTVVDIGQGDSIFLRDIQGRTVLIDVGGRVDFTVKEGWKARSRQANAERTLIPYLHSRGVDKIDSLVLTHTDTD
HVGDVLEVAKNFKIGKIYVSSGSLTVPSFVTTLKKINVPVHVVQVGDRLPIVDSYLEVLYPSRSGDGSNNDSIVLYGRLL
GINFLFTGDLEEGELELIKTYPKLSVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGEKNRYKHPHQETLERFEQKNMQ
IYRTDRQGAIRFRGWRSWSIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=91142 SUT_RS06955 WP_237373048.1 1463137..1465371(-) (comEC/celB) [Streptococcus ruminantium strain GUT-183]
ATGTTACGGTTGGATAAGCTTCCCTGTCAGCCTATACATCTAGCCATTTTGGCGGTCGTGACCTACTTTACGGTTCACCG
TTTTTCGATGTTGACAATGAGCCTTCTGATATTATTATTGATAATCTTTTGGAGACGTCAGGGGAAACTTACTTTTTTTA
AAATGCTGCCGCTTCTAGTCTTATGCGGTCTATTCTTCGGCTGCCAAAAGCTCAAATGGAAACAGGAAGAGCAAGCTGTT
TCAAAGCAAGTGACTGCTGTAGAGATTGTGCCGGATACTATAAATATCAATGGCGATCAGTTATCTTTCCGTGCTAGGAC
TGATGGTCAGATTTATCAAGGTTTCTATAAGCTAACTAGTCAGAAAGAACAGGAGTATTTCCAAAAGCTAACAGCTCTTG
TTCAGGTGGAGGTGAAGGCAGAGACGAGTCTCCCATCAGGTCAGCGGAATTTCAATGGTTTTGATTATCAAGCCTATTTA
AAAACACAGGGAATCTATCGAATCCTCACCATAGCGACTATCAATAAGATCGTACCTATTCACTCTTGGAACCCTATGGA
TTGGTTGTCAATTTGGCGGAGAAAAGCCTTGGTTTTCATCAAATCTAATTTTCCTTCCCCCATGAGCCATTACATGACAG
GGTTGCTTTTTGGAGAGTTGGACAGTGACTTTGATCAGATGAGCGCCCTTTATTCCAGTCTGGGGATTATCCATCTCTTT
GCTCTATCAGGAATGCAGGTAGGTTTTTTCATTGATAAGTTTCGCTGGATTTTACTGCGTTTAGGCTTGACAAAGGAGAC
AGTTGATCAATTACAAGTCCCCTTTTCTTTGGTCTATGCTGGTTTGACAGGCTTTTCTGTATCAGTCGTCCGGTCTTTGA
TTCAGAAAATTTTGAGCAACCTGGGGCTTCGGAAGCTGGATAATTTTGCTGCAACACTCTTTATTTGTTTCTTGGTGCAG
CCTCGTTTTCTCCTGACAGTTGGAGGTGTCTTGACATTTACCTATGCTTTTTTGTTGACAGTCTTTGATTTTGAGGATTT
GAAGCAAATCAAAAAGGTTGTAGTGGAAAGTCTGAGTATTTCTCTGGGGATTCTGCCAATTCTGATGACCTATTTTTACG
CTTTTCAGCCCCTATCTATTCTACTAACCTTCTTCTTTTCCTTTGTTTTTGATGTATTGCTTTTGCCGAGTCTATCTGTA
ATTTTTCTTTTATCTCCCTTGGTCAAGATTACTTGGGTCAATTCTTTCTTTGTTTTGATGGAGAAAATGATTATTTGGGT
ATCGGATTTGGGTCTTCGACCTTTGATACTAGGGAAACCGTCTGACTTCATCTTGTTAGTTTTGTTACTGGGATTTTTCA
TGCTTTACGATTTTCATAGACAGAAAAAATGGCTGTTAGGACTGAGTTTGCTCCTTACTCTGCTATTTTTCATTACAAAA
CATCCATTAGAAAATGAAGTAACTGTGGTAGATATCGGACAGGGAGATAGTATCTTTTTGCGAGATATACAGGGGCGTAC
GGTTCTAATTGACGTTGGTGGACGGGTGGATTTTACGGTCAAGGAAGGCTGGAAGGCGCGATCCCGTCAGGCTAATGCAG
AGAGGACCTTGATTCCTTATCTACATAGTCGAGGTGTGGACAAGATTGACAGTTTGGTGTTGACGCACACCGATACTGAC
CATGTGGGCGATGTTCTGGAAGTAGCTAAGAATTTTAAGATCGGAAAAATCTATGTGTCTTCAGGTAGTTTGACAGTCCC
TAGCTTTGTAACCACCTTGAAAAAAATCAATGTACCTGTTCATGTGGTGCAGGTGGGTGATCGCCTACCGATTGTTGATT
CCTATTTGGAAGTGCTCTATCCGAGCCGATCGGGTGATGGTAGCAACAATGATTCTATTGTCCTCTATGGACGGCTCCTT
GGAATCAATTTTCTGTTTACGGGTGATCTGGAGGAGGGGGAATTAGAGCTGATAAAAACCTATCCCAAATTGTCAGTTGA
TGTTCTAAAAGCCGGACACCATGGTTCAAAAGGTTCTTCTTATCCTGAATTTTTAGACCATATTGGAGCTAAGATTGCCT
TAATCTCGGCTGGCGAGAAAAATCGCTACAAGCATCCCCATCAAGAAACCTTGGAGCGTTTTGAACAGAAGAATATGCAA
ATCTATCGGACAGACCGGCAAGGAGCTATTCGCTTTAGAGGTTGGCGAAGTTGGTCAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-459)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.681	100	0.539
comEC/celB	Streptococcus mitis NCTC 12261	53.1	99.731	0.53
comEC/celB	Streptococcus pneumoniae TIGR4	51.952	99.866	0.519
comEC/celB	Streptococcus pneumoniae Rx1	51.413	99.866	0.513
comEC/celB	Streptococcus pneumoniae D39	51.413	99.866	0.513
comEC/celB	Streptococcus pneumoniae R6	51.413	99.866	0.513
comEC	Lactococcus lactis subsp. cremoris KW2	47.779	99.866	0.477