Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SM123_RS07330 Genome accession   NZ_CP139419
Coordinates   1533609..1534277 (-) Length   222 a.a.
NCBI ID   WP_320909342.1    Uniprot ID   -
Organism   Streptococcus lingualis strain S5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1528609..1539277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS07310 (SM123_07310) sodA 1528952..1529557 (-) 606 WP_195529528.1 superoxide dismutase SodA -
  SM123_RS07315 (SM123_07315) holA 1529646..1530680 (-) 1035 WP_320909340.1 DNA polymerase III subunit delta -
  SM123_RS07320 (SM123_07320) - 1530704..1531306 (-) 603 WP_223325348.1 DUF805 domain-containing protein -
  SM123_RS07325 (SM123_07325) comEC/celB 1531382..1533628 (-) 2247 WP_320909341.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SM123_RS07330 (SM123_07330) comEA/celA/cilE 1533609..1534277 (-) 669 WP_320909342.1 helix-hairpin-helix domain-containing protein Machinery gene
  SM123_RS07335 (SM123_07335) - 1534345..1535091 (-) 747 WP_003006324.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SM123_RS07340 (SM123_07340) - 1535267..1537606 (+) 2340 WP_320909343.1 cation-translocating P-type ATPase -
  SM123_RS07345 (SM123_07345) - 1537638..1538168 (-) 531 WP_021152864.1 DUF4352 domain-containing protein -
  SM123_RS07350 (SM123_07350) - 1538308..1539054 (+) 747 WP_320909344.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23856.67 Da        Isoelectric Point: 5.1563

>NTDB_id=909542 SM123_RS07330 WP_320909342.1 1533609..1534277(-) (comEA/celA/cilE) [Streptococcus lingualis strain S5]
MEDIIEKIKEYKLFLALTAIGLLLGGYFLFHRPQSSASTIPDLYQSSSSTSSKEKVQTNSSKEEKTATSVSDAPEIITVD
VKGAVKQPGVYELRSNSRVHDAIYKAGGMTADANSQSVNLAQKLSDEAVIYVAKEGEDVPVLGSSESPATSSAPAEKTGK
VHLNRATESDLQTVSGIGQKRAQDIIAYREANGPFRSVDDLKNVSGIGEKTLEKLRDAFTVD

Nucleotide


Download         Length: 669 bp        

>NTDB_id=909542 SM123_RS07330 WP_320909342.1 1533609..1534277(-) (comEA/celA/cilE) [Streptococcus lingualis strain S5]
ATGGAGGATATCATCGAAAAAATCAAAGAATATAAGCTCTTTTTAGCTCTTACTGCTATCGGACTCTTACTTGGAGGGTA
TTTTCTTTTTCATCGACCTCAGTCAAGTGCATCCACCATACCGGATCTTTATCAGTCTTCTAGTTCAACTTCGAGCAAAG
AAAAGGTGCAGACTAATAGTTCCAAAGAAGAAAAGACGGCGACTTCTGTGTCTGATGCACCCGAGATCATTACGGTCGAT
GTCAAAGGAGCCGTCAAACAACCAGGGGTCTATGAGTTGCGCTCCAATAGCAGAGTCCACGATGCTATTTATAAGGCGGG
TGGGATGACAGCAGATGCCAATAGCCAATCGGTCAACTTGGCGCAAAAACTCTCCGATGAAGCAGTGATCTATGTTGCTA
AAGAAGGAGAGGATGTTCCAGTACTTGGAAGTTCAGAAAGTCCTGCAACTTCGTCAGCGCCAGCAGAAAAAACAGGCAAA
GTCCATTTAAATCGAGCGACCGAGTCAGATCTCCAGACAGTATCAGGCATTGGCCAGAAACGTGCCCAGGACATTATCGC
CTATCGCGAAGCAAATGGTCCTTTTCGATCAGTGGATGATCTGAAGAATGTTTCAGGAATCGGAGAGAAAACACTGGAGA
AACTAAGAGATGCTTTCACGGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(158-219)

SLBB domain (SLBB)

(79-132)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.889

100

0.495
  comEA/celA/cilE Streptococcus mitis SK321

47.807

100

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

48.649

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.649

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae D39

48.649

100

0.486
  comEA Streptococcus thermophilus LMD-9

44.737

100

0.459
  comEA Lactococcus lactis subsp. cremoris KW2

42.672

100

0.446
  comEA Staphylococcus aureus MW2

36.323

100

0.365