Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SM123_RS07325 Genome accession   NZ_CP139419
Coordinates   1531382..1533628 (-) Length   748 a.a.
NCBI ID   WP_320909341.1    Uniprot ID   -
Organism   Streptococcus lingualis strain S5     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1526382..1538628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS07305 (SM123_07305) - 1527269..1528741 (-) 1473 WP_320909339.1 helicase HerA-like domain-containing protein -
  SM123_RS07310 (SM123_07310) sodA 1528952..1529557 (-) 606 WP_195529528.1 superoxide dismutase SodA -
  SM123_RS07315 (SM123_07315) holA 1529646..1530680 (-) 1035 WP_320909340.1 DNA polymerase III subunit delta -
  SM123_RS07320 (SM123_07320) - 1530704..1531306 (-) 603 WP_223325348.1 DUF805 domain-containing protein -
  SM123_RS07325 (SM123_07325) comEC/celB 1531382..1533628 (-) 2247 WP_320909341.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SM123_RS07330 (SM123_07330) comEA/celA/cilE 1533609..1534277 (-) 669 WP_320909342.1 helix-hairpin-helix domain-containing protein Machinery gene
  SM123_RS07335 (SM123_07335) - 1534345..1535091 (-) 747 WP_003006324.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SM123_RS07340 (SM123_07340) - 1535267..1537606 (+) 2340 WP_320909343.1 cation-translocating P-type ATPase -
  SM123_RS07345 (SM123_07345) - 1537638..1538168 (-) 531 WP_021152864.1 DUF4352 domain-containing protein -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 85829.39 Da        Isoelectric Point: 9.3821

>NTDB_id=909541 SM123_RS07325 WP_320909341.1 1531382..1533628(-) (comEC/celB) [Streptococcus lingualis strain S5]
MLSRWIKDLPFSLVHLAFLLLWLYFSIYQPSWLSISGLVVVGVLAVHHYKGDRSSLLGLGLVTLCFAAFFVFQRLQDHPV
QVESQPPPHLRLIPDTIKINGDALSFRAKNQGRTYQVFYTLKSEKEKQQWQSQTHLLELTYKGVIEEPEGQRNFRGFDYR
AYLQTQGIHYQIKIEAIQSALPIQTWNVFDWLSQWRRQAIVWSKEHFPQPMNQYMTGLLFGYLDKDFEEMDQLYTSLGII
HLFALSGMQVGFFINGIRKALLRLGILQETVDIWMLPISLVYAGLTGFSVSVVRSLLQKILSQKGIRGMENMAMTLMLLM
FLMPKFLLTAGGVLSCAYAFILTLVDTSSYSGLKKLLVESLWISLGILPLLTYYFSVFQPWSLPLTFLFSFLFDLVLLPG
LTVLFILSILKPLTIFNSFFLLIEECIRWISKLTSLPLVFGQPTGPALIALFLLFGILYDLRKQKKRRFLLIGMILLIFC
WTKHPLENEITMVDIGQGDSIFLRDWKGRTLLIDVGGRVTFKSGDKWQERSQSANAEQTLIPYLKSRGVGKLDALVLTHT
DQDHMGDMVEVAKQIPVKKVYVSPGSLTNSQFREKLKQLHSPIKVVQRGDQLPIFDDHLEVLSPDEVGEGKNDDSIVLYG
QFYQKRFLFTGDLEEAGEKKLLKNDPQLQVDVLKVGHHGSKGSSSDVFLDQLHPQLALISVGKKNRYQHPHKELLDRLEE
RSISYFRTDERGAIRLIGWNHWRVETVR

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=909541 SM123_RS07325 WP_320909341.1 1531382..1533628(-) (comEC/celB) [Streptococcus lingualis strain S5]
ATGCTTTCACGGTGGATTAAAGACCTTCCATTTTCTCTTGTCCATCTCGCCTTTTTGCTCCTATGGCTGTATTTTAGTAT
CTATCAACCATCTTGGCTTTCGATCAGCGGTCTAGTAGTAGTGGGAGTTTTAGCGGTTCATCACTATAAAGGGGATCGCT
CAAGTTTGCTAGGGCTTGGTTTAGTAACCCTTTGTTTCGCGGCCTTCTTTGTCTTTCAGCGACTACAGGATCATCCAGTA
CAAGTGGAAAGTCAGCCCCCACCCCACTTACGCCTGATTCCAGATACGATCAAGATCAATGGGGATGCCCTGTCTTTTCG
TGCTAAAAATCAGGGTAGGACCTATCAAGTCTTCTACACTTTAAAATCAGAAAAAGAAAAACAGCAGTGGCAAAGTCAAA
CTCATTTGTTGGAGTTGACATATAAAGGTGTTATAGAGGAACCAGAAGGACAGCGAAATTTTAGAGGATTTGACTACCGG
GCTTATTTGCAAACACAGGGGATTCACTATCAAATAAAAATTGAAGCGATCCAATCCGCGCTTCCTATACAGACTTGGAA
TGTTTTTGACTGGCTGTCTCAATGGAGGCGACAAGCCATTGTTTGGAGTAAAGAGCACTTTCCGCAGCCAATGAACCAGT
ATATGACCGGCCTTCTTTTTGGCTATTTAGATAAGGATTTTGAAGAGATGGACCAGCTTTACACGAGTTTAGGAATCATC
CATTTATTCGCCTTATCTGGGATGCAGGTCGGCTTTTTCATCAATGGGATCCGGAAAGCTCTCTTACGTCTAGGAATCTT
GCAAGAAACAGTTGATATCTGGATGCTTCCAATTTCTTTGGTCTATGCTGGCTTGACAGGTTTTTCAGTTTCAGTGGTTC
GCAGTCTCTTGCAGAAGATTCTCTCTCAAAAGGGCATCCGAGGGATGGAGAATATGGCGATGACCTTGATGCTCTTAATG
TTTCTCATGCCCAAGTTTCTCCTGACAGCTGGAGGGGTTTTGAGTTGTGCCTACGCCTTTATTTTGACCTTGGTAGATAC
CAGTTCTTATTCCGGACTGAAAAAGCTACTAGTGGAAAGTTTATGGATTAGCCTGGGGATTTTGCCCCTTTTGACCTATT
ACTTTAGTGTCTTTCAACCGTGGTCACTCCCTTTAACCTTCCTCTTTTCTTTCTTATTTGATCTTGTCCTTCTTCCAGGT
TTAACGGTGCTATTTATCTTATCGATTCTAAAGCCCCTTACAATTTTTAACAGTTTCTTTCTTCTCATAGAGGAGTGTAT
TCGTTGGATTTCAAAGCTCACGTCGCTACCTTTGGTATTTGGTCAGCCGACGGGACCAGCTCTGATTGCTCTCTTCCTTC
TTTTTGGGATCTTGTATGATCTTCGAAAGCAAAAAAAACGTCGTTTTCTGTTAATCGGTATGATTCTACTCATCTTTTGT
TGGACCAAGCACCCTTTAGAAAATGAGATTACCATGGTGGATATCGGTCAAGGAGACAGTATCTTTTTACGCGATTGGAA
AGGAAGAACCCTATTGATTGATGTTGGAGGACGTGTCACTTTTAAAAGTGGAGACAAGTGGCAAGAGCGCAGTCAATCTG
CCAATGCGGAACAAACCTTGATTCCCTATCTCAAGAGTCGAGGTGTTGGAAAACTCGATGCTTTGGTCTTGACTCATACA
GACCAGGACCATATGGGCGATATGGTGGAGGTTGCCAAACAAATCCCGGTTAAAAAAGTGTATGTCAGTCCAGGTAGTCT
AACTAATTCTCAATTTCGAGAGAAATTGAAACAGCTTCATAGTCCGATTAAAGTAGTCCAGAGAGGAGATCAACTACCTA
TTTTTGATGATCATTTAGAAGTCTTATCCCCTGATGAAGTGGGGGAAGGTAAAAATGATGATTCGATTGTCCTCTATGGG
CAGTTCTATCAGAAACGATTTTTGTTCACAGGTGATCTGGAAGAAGCCGGAGAGAAGAAACTATTGAAAAACGATCCACA
ATTACAAGTAGATGTCTTGAAAGTAGGCCACCACGGTTCTAAAGGTTCCTCTAGTGATGTGTTTTTAGATCAGTTACATC
CTCAGTTGGCCTTGATCTCTGTTGGAAAGAAAAATCGCTACCAGCATCCTCACAAAGAATTGCTCGATCGTCTAGAGGAA
CGCTCTATTTCTTATTTTCGTACCGATGAAAGGGGAGCGATTCGCTTGATTGGATGGAACCATTGGAGGGTAGAAACGGT
CCGCTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(218-462)

Metallo-beta-lactamase superfamily (Lactamase_B)

(496-700)

Domain of unknown function (DUF4131) (DUF4131)

(28-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.672

100

0.537
  comEC/celB Streptococcus mitis NCTC 12261

52.941

100

0.529
  comEC/celB Streptococcus pneumoniae TIGR4

52.603

100

0.527
  comEC/celB Streptococcus pneumoniae Rx1

52.336

100

0.524
  comEC/celB Streptococcus pneumoniae D39

52.336

100

0.524
  comEC/celB Streptococcus pneumoniae R6

52.336

100

0.524
  comEC Lactococcus lactis subsp. cremoris KW2

46.996

100

0.471