Detailed information NTG0909517

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: SM123_RS01220
• Genome accession: NZ_CP139419
• Coordinates: 225415..226683 (+)
• Length: 422 a.a.
• NCBI ID: WP_320909634.1
• Uniprot ID: -
• Organism: Streptococcus lingualis strain S5
• Function: facilitate localization of RecA (predicted from homology) Homologous recombination

Genomic Context

Location: 220415..231683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SM123_RS01200 (SM123_01200)	mutL	220815..222758 (+)	1944	WP_070594641.1	DNA mismatch repair endonuclease MutL	-
SM123_RS01205 (SM123_01205)	ruvA	222779..223372 (+)	594	WP_070661626.1	Holliday junction branch migration protein RuvA	-
SM123_RS01210 (SM123_01210)	-	223382..223945 (+)	564	WP_070594639.1	DNA-3-methyladenine glycosylase I	-
SM123_RS01215 (SM123_01215)	-	224008..225039 (-)	1032	WP_320909633.1	S66 peptidase family protein	-
SM123_RS01220 (SM123_01220)	cinA	225415..226683 (+)	1269	WP_320909634.1	competence/damage-inducible protein A	Machinery gene
SM123_RS01225 (SM123_01225)	recA	226804..227949 (+)	1146	WP_003002082.1	recombinase RecA	Machinery gene
SM123_RS01230 (SM123_01230)	spx	228037..228435 (+)	399	WP_003009108.1	transcriptional regulator Spx	-
SM123_RS01235 (SM123_01235)	-	228572..229168 (+)	597	WP_201087716.1	SP0191 family lipoprotein	-
SM123_RS01240 (SM123_01240)	-	229293..229559 (+)	267	WP_003002070.1	IreB family regulatory phosphoprotein	-
SM123_RS01245 (SM123_01245)	ruvX	229559..229978 (+)	420	WP_023919889.1	Holliday junction resolvase RuvX	-
SM123_RS01250 (SM123_01250)	-	230001..230306 (+)	306	WP_003001941.1	DUF1292 domain-containing protein	-

Sequence

Protein

• Length: 422 a.a.
• Molecular weight: 45111.28 Da
• Isoelectric Point: 4.8690

>NTDB_id=909517 SM123_RS01220 WP_320909634.1 225415..226683(+) (cinA) [Streptococcus lingualis strain S5]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYYHVAVGDNEGRLFSTIETASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDPTALAKLDTFFASRPDYVRTPNNERQAQLIAGSIPLQNRTGLAVGGLIEVDGVTYVVLPGPPSELKPM
VNEQLVPHLTTGEQLFSRVLRFFGIGESQLVTILADIIEEQSDPTVAPYAKTGEVTLRLSTKAKDQASADAKLDVLEKEI
LSRHTLDHQPLHELFYGYGDDNSMAKVAFDLLKRTGKTITAAESLTAGLFQATLADFSGASSIFAGGFVTYSLEEKSKML
SIPAQELEQHGVVSHFTAQAMASQARKLTGSDYGVSLTGVAGPDSLEGHPAGTVFIGLATPNGVDSVQVNIAGRSRADVR
EIAVLHAFNLVRLAVLNGENLV

Nucleotide

• Length: 1269 bp

>NTDB_id=909517 SM123_RS01220 WP_320909634.1 225415..226683(+) (cinA) [Streptococcus lingualis strain S5]
ATGAAGGCGGAAATTATTGCAGTTGGAACAGAAATTCTAACAGGACAAATTGTGAACACCAATGCTCAATTCTTGTCTGA
AAAATTGGCTAGTTTAGGGATTGATGTCTATTATCATGTGGCGGTAGGAGACAATGAAGGTCGTCTCTTCTCGACCATTG
AGACAGCTTCAAAACGCAGTGATTTGGTGATTTTATGTGGTGGACTTGGGCCAACAGAGGATGATTTGACCAAGCAAACC
CTTGCTAAGTTTTTAGGGAAAGAACTGGTTTTTGATCCAACAGCGCTTGCCAAACTCGACACCTTCTTTGCCAGTCGCCC
TGATTATGTCCGGACGCCCAATAATGAGCGGCAAGCACAATTGATTGCCGGTTCAATCCCCCTTCAAAACCGTACAGGTC
TCGCGGTTGGAGGTTTGATTGAAGTCGACGGTGTGACCTATGTCGTTCTACCTGGTCCACCAAGTGAGTTAAAACCCATG
GTCAATGAACAATTGGTGCCTCATTTGACAACAGGGGAACAGCTCTTTTCAAGAGTCTTGCGCTTCTTTGGAATTGGGGA
AAGCCAGCTGGTTACGATCCTAGCAGATATCATTGAAGAGCAGAGTGATCCGACAGTTGCCCCTTATGCCAAGACAGGAG
AAGTAACCTTGCGTCTATCTACAAAGGCGAAGGATCAAGCCTCAGCGGATGCGAAGCTCGATGTCTTAGAAAAGGAAATC
TTATCCCGTCATACGCTGGATCATCAACCCTTGCATGAACTGTTTTACGGTTATGGGGATGATAATTCGATGGCCAAGGT
GGCCTTTGATCTCTTGAAACGGACTGGTAAGACCATTACAGCTGCAGAAAGCCTGACAGCTGGCCTTTTCCAAGCGACTT
TGGCAGATTTTTCAGGTGCGTCCAGCATCTTCGCAGGTGGTTTTGTCACCTATAGTCTGGAAGAAAAAAGCAAGATGTTG
TCTATTCCAGCTCAAGAGTTAGAGCAACATGGAGTGGTGTCTCATTTTACAGCTCAAGCCATGGCTTCACAGGCCCGTAA
GTTAACAGGATCCGATTATGGTGTTAGCCTGACCGGAGTTGCGGGGCCAGATAGTCTAGAAGGGCATCCAGCAGGGACTG
TCTTTATCGGACTTGCGACTCCAAATGGAGTAGATAGTGTCCAAGTCAATATCGCCGGACGTAGCCGGGCGGATGTCCGC
GAAATTGCAGTCCTTCATGCCTTTAATTTGGTACGCTTGGCTGTATTAAATGGTGAAAATTTGGTATAA

Domains

Predicted by InterproScan.

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

• Competence-damaged protein (CinA) (262-412)

• Damage-inducible protein CinA KH domain (CinA_KH) (177-243)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mitis NCTC 12261	75.06	98.815	0.742
cinA	Streptococcus mitis SK321	74.82	98.815	0.739
cinA	Streptococcus pneumoniae Rx1	73.861	98.815	0.73
cinA	Streptococcus pneumoniae R6	73.861	98.815	0.73
cinA	Streptococcus pneumoniae TIGR4	73.861	98.815	0.73
cinA	Streptococcus pneumoniae D39	73.621	98.815	0.727
cinA	Streptococcus mutans UA159	70.686	100	0.709
cinA	Streptococcus suis isolate S10	55.69	97.867	0.545
cinA	Bacillus subtilis subsp. subtilis str. 168	47.47	98.341	0.467