Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SKB18_RS05145 Genome accession   NZ_CP139163
Coordinates   1047543..1048724 (-) Length   393 a.a.
NCBI ID   WP_012774894.1    Uniprot ID   -
Organism   Streptococcus suis strain cnzyss2-311     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1042543..1053724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SKB18_RS05105 rpsJ 1042832..1043140 (-) 309 WP_011922546.1 30S ribosomal protein S10 -
  SKB18_RS05110 comX/sigX 1043464..1043730 (-) 267 WP_014635810.1 hypothetical protein Regulator
  SKB18_RS05115 - 1043803..1044381 (-) 579 WP_012774895.1 nucleotidyltransferase family protein -
  SKB18_RS05120 - 1044589..1044909 (-) 321 WP_002939343.1 DUF1292 domain-containing protein -
  SKB18_RS05125 ruvX 1044921..1045340 (-) 420 WP_079254804.1 Holliday junction resolvase RuvX -
  SKB18_RS05130 - 1045340..1045606 (-) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  SKB18_RS05135 spx 1045706..1046104 (-) 399 WP_002939362.1 transcriptional regulator Spx -
  SKB18_RS05140 recA 1046340..1047491 (-) 1152 WP_011922545.1 recombinase RecA Machinery gene
  SKB18_RS05145 cinA 1047543..1048724 (-) 1182 WP_012774894.1 competence/damage-inducible protein A Machinery gene
  SKB18_RS05150 - 1048761..1049330 (-) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  SKB18_RS05155 ruvA 1050055..1050645 (-) 591 WP_011921679.1 Holliday junction branch migration protein RuvA -
  SKB18_RS05160 mutL 1050684..1052621 (-) 1938 WP_012774891.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42862.76 Da        Isoelectric Point: 4.3975

>NTDB_id=907456 SKB18_RS05145 WP_012774894.1 1047543..1048724(-) (cinA) [Streptococcus suis strain cnzyss2-311]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADVIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=907456 SKB18_RS05145 WP_012774894.1 1047543..1048724(-) (cinA) [Streptococcus suis strain cnzyss2-311]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTTCATACGGCAGTTGGTGACAATGAAGGCCGTTTATTATCAACCCTTG
AAGTAGCCAGCAAGCGGAGTAATATGGTCGTTCTTTGCGGTGGTTTAGGACCAACTGAGGACGACCTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACGTGATTGATAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCGTCGGTCAGCTAGGGATAGAATCGGGCTGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(258-392)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

100

100

1
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus mitis SK321

54.808

100

0.58
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus mutans UA159

55.474

100

0.58
  cinA Streptococcus mitis NCTC 12261

54.567

100

0.578
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

41.379

95.929

0.397