NTDB

Overview

Name	comGC	Type	Machinery gene
Locus tag	SGW66_RS02595	Genome accession	NZ_CP138669
Coordinates	468368..468679 (+)	Length	103 a.a.
NCBI ID	WP_000472255.1	Uniprot ID	A0A0U1MLR1
Organism	Staphylococcus aureus strain DA70710
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 463368..473679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGW66_RS02565	-	464151..464354 (+)	204	WP_000087561.1	YqgQ family protein	-
SGW66_RS02570	-	464351..465337 (+)	987	WP_000161307.1	ROK family glucokinase	-
SGW66_RS02575	-	465337..465666 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
SGW66_RS02580	-	465663..466286 (+)	624	WP_001223009.1	MBL fold metallo-hydrolase	-
SGW66_RS02585	comGA	466338..467312 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
SGW66_RS02590	comGB	467284..468354 (+)	1071	WP_000776409.1	competence type IV pilus assembly protein ComGB	Machinery gene
SGW66_RS02595	comGC	468368..468679 (+)	312	WP_000472255.1	competence type IV pilus major pilin ComGC	Machinery gene
SGW66_RS02600	comGD	468657..469103 (+)	447	WP_001796473.1	competence type IV pilus minor pilin ComGD	Machinery gene
SGW66_RS02605	comGE	469090..469389 (+)	300	WP_000844413.1	hypothetical protein	Machinery gene
SGW66_RS02610	comGF	469307..469804 (+)	498	WP_001796472.1	competence type IV pilus minor pilin ComGF	Machinery gene
SGW66_RS02615	-	469901..470047 (+)	147	WP_001789879.1	hypothetical protein	-
SGW66_RS02620	-	470037..470561 (+)	525	WP_001015120.1	shikimate kinase	-
SGW66_RS02625	gcvT	470720..471811 (+)	1092	WP_000093344.1	glycine cleavage system aminomethyltransferase GcvT	-
SGW66_RS02630	gcvPA	471831..473177 (+)	1347	WP_000019698.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

Download Length: 103 a.a. Molecular weight: 11301.33 Da Isoelectric Point: 8.5268

                                >NTDB_id=904418 SGW66_RS02595 WP_000472255.1 468368..468679(+) (comGC) [Staphylococcus aureus strain DA70710]

MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI

KEAQKTCKSGESITISNGEAVAN

Nucleotide

Download Length: 312 bp

                                >NTDB_id=904418 SGW66_RS02595 WP_000472255.1 468368..468679(+) (comGC) [Staphylococcus aureus strain DA70710]

ATGTTTAAATTTCTAAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT

AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA

ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA

AAAGAAGCACAAAAGACATGTAAATCAGGAGAGTCAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-30)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0U1MLR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGC	Staphylococcus aureus N315	99.029	100	0.99
comGC	Staphylococcus aureus MW2	99.029	100	0.99
comGC/cglC	Streptococcus mitis SK321	47.059	99.029	0.466
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comYC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comYC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369

Detailed information NTG0904418