Detailed information NTG0896158

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R4701_RS02605
• Genome accession: NZ_CP137114
• Coordinates: 519810..520592 (+)
• Length: 260 a.a.
• NCBI ID: WP_317805978.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15P3054
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 514810..525592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4701_RS02565	-	515441..515799 (-)	359	Protein_509	immunity protein	-
R4701_RS02570	-	516280..516399 (-)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
R4701_RS02575	cipB	516503..516652 (-)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator
R4701_RS02580	blpK	516896..517144 (-)	249	WP_000379965.1	bacteriocin-like peptide BlpK	-
R4701_RS02585	blpJ	517213..517482 (-)	270	WP_001093250.1	bacteriocin-like peptide BlpJ	-
R4701_RS02590	blpI	517949..518146 (-)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
R4701_RS02595	comA/nlmT	518435..519022 (+)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
R4701_RS02600	comA/nlmT	518967..519773 (+)	807	WP_317805977.1	ABC transporter transmembrane domain-containing protein	Regulator
R4701_RS02605	comA/nlmT	519810..520592 (+)	783	WP_317805978.1	ATP-binding cassette domain-containing protein	Regulator
R4701_RS02610	-	520603..521964 (+)	1362	WP_001069085.1	bacteriocin secretion accessory protein	-
R4701_RS02615	blpC	522021..522176 (+)	156	WP_000358810.1	quorum-sensing system pheromone BlpC	-
R4701_RS02620	-	522221..523561 (-)	1341	WP_317805979.1	sensor histidine kinase	-
R4701_RS02625	comE/blpR	523575..524312 (-)	738	WP_001219121.1	response regulator transcription factor	Regulator
R4701_RS02630	-	524317..524655 (-)	339	WP_000876675.1	LytTR family DNA-binding domain-containing protein	-
R4701_RS02635	-	524931..525260 (+)	330	WP_000132572.1	hypothetical protein	-

Sequence

Protein

• Length: 260 a.a.
• Molecular weight: 29297.58 Da
• Isoelectric Point: 6.5017

>NTDB_id=896158 R4701_RS02605 WP_317805978.1 519810..520592(+) (comA/nlmT) [Streptococcus pneumoniae strain 15P3054]
MNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPY
KGHISINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSD
GAGLSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIE
VGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 783 bp

>NTDB_id=896158 R4701_RS02605 WP_317805978.1 519810..520592(+) (comA/nlmT) [Streptococcus pneumoniae strain 15P3054]
TTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATAT
TGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAG
ATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTAC
AAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACC
CCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATA
TTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGAT
GGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACT
AGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCTAACTGATAAAACCA
TTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAA
GTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (43-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.656	99.615	0.704
comA	Streptococcus pneumoniae Rx1	64.615	100	0.646
comA	Streptococcus pneumoniae D39	64.615	100	0.646
comA	Streptococcus pneumoniae R6	64.615	100	0.646
comA	Streptococcus mitis NCTC 12261	64.615	100	0.646
comA	Streptococcus pneumoniae TIGR4	64.231	100	0.642
comA	Streptococcus gordonii str. Challis substr. CH1	63.359	100	0.638
comA	Streptococcus mitis SK321	63.462	100	0.635