Detailed information NTG0896046

Bioinformatically predicted

Overview

• Name: radA
• Type: Machinery gene
• Locus tag: R4700_RS05725
• Genome accession: NZ_CP137112
• Coordinates: 1109818..1111179 (+)
• Length: 453 a.a.
• NCBI ID: WP_073176637.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 02H2025
• Function: homologous recombination (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1112111..1113462	1109818..1111179	flank	932

Gene organization within MGE regions

Location: 1109818..1113462

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4700_RS05725	radA	1109818..1111179 (+)	1362	WP_073176637.1	DNA repair protein RadA	Machinery gene
R4700_RS05730	-	1111252..1111749 (+)	498	WP_001809263.1	carbonic anhydrase	-
R4700_RS05735	-	1111770..1112057 (+)	288	Protein_1082	PrsW family intramembrane metalloprotease	-
R4700_RS05740	-	1112111..1113462 (+)	1352	WP_088778796.1	IS3 family transposase	-

Sequence

Protein

• Length: 453 a.a.
• Molecular weight: 49446.98 Da
• Isoelectric Point: 6.5137

>NTDB_id=896046 R4700_RS05725 WP_073176637.1 1109818..1111179(+) (radA) [Streptococcus pneumoniae strain 02H2025]
MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKNARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRV
LGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAK
RTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGELGLTGEIR
RVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKKVFA

Nucleotide

• Length: 1362 bp

>NTDB_id=896046 R4700_RS05725 WP_073176637.1 1109818..1111179(+) (radA) [Streptococcus pneumoniae strain 02H2025]
ATCGCAAAGAAAAAAGCGACATTTGTATGTCAAAATTGTGGGTATAATTCCCCTAAATATCTGGGACGTTGCCCCAACTG
TGGGTCTTGGTCTTCTTTTGTGGAAGAGGTTGAGGTTGCCGAGGTCAAGAATGCGCGTGTGTCCTTGACAGGTGAGAAAA
CCAAGCCCATGAAACTAGCTGAGGTGACTTCCATCAATGTCAATCGAACCAAGACGGAGATGGAGGAATTCAACCGTGTG
CTTGGAGGCGGAGTGGTACCAGGAAGTCTCGTCCTCATCGGTGGGGATCCTGGGATTGGGAAATCAACTCTTCTCCTACA
AGTCTCAACCCAGTTGTCCCAAGTGGGGACAGTTCTCTATATCAGTGGGGAGGAGTCTGCCCAGCAGATTAAACTACGTG
CAGAGCGCTTAGGTGATATTGATAGTGAGTTTTATCTCTATGCAGAGACCAATATGCAGAGTGTTCGTGCAGAAGTGGAG
CGTATCCAGCCAGACTTTCTTATTATTGATTCCATCCAGACCATCATGTCTCCTGAGATTTCAGGGGTGCAGGGGTCTGT
TTCTCAGGTACGTGAAGTGACCGCTGAACTCATGCAGTTGGCCAAGACCAATAACATTGCCATCTTTATCGTAGGTCATG
TGACCAAAGAAGGAACCTTGGCTGGGCCTCGTATGTTGGAGCATATGGTGGATACGGTGCTTTACTTTGAAGGGGAGCGT
CACCACACCTTTCGTATTTTGAGAGCGGTCAAAAATCGTTTTGGTTCCACTAATGAGATTGGGATTTTTGAGATGCAGTC
GGGCGGCTTGGTTGAGGTACTCAATCCGAGTCAAGTTTTCCTAGAAGAGCGTTTGGATGGGGCAACTGGTTCCTCCATCG
TTGTAACCATGGAAGGGACGCGTCCGATTTTGGCGGAGGTTCAGGCTTTGGTAACACCGACCATGTTTGGAAATGCCAAG
CGTACTACGACAGGACTTGATTTTAACCGTGCTAGCTTGATTATGGCTGTTTTGGAAAAACGGGCAGGGCTTCTCTTGCA
AAATCAGGATGCCTATCTCAAATCTGCTGGTGGTGTTAAATTGGATGAACCTGCCATTGACTTGGCTGTTGCAGTTGCTA
TTGCTTCGAGCTACAAAGACAAGCCAACTAATCCTCAGGAATGTTTTGTCGGAGAACTGGGCTTGACAGGAGAGATTCGG
CGCGTGAATCGTATTGAGCAACGCATCAACGAAGCTGCTAAACTGGGCTTTACTAAGATTTATGTACCTAAGAATTCCTT
GACAGGAATCACTCTGCCTAAGGAAATTCAGGTCATTGGCGTGACAACGATTCAGGAAGTTTTGAAAAAGGTCTTTGCAT
AA

Domains

Predicted by InterproScan.

• Rubredoxin metal binding domain (Zn_ribbon_LapB) (8-35)

• Subunit ChlI of Mg-chelatase (ChlI) (360-425)

• AAA domain (AAA_25) (63-218)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
radA	Streptococcus pneumoniae Rx1	99.779	100	0.998
radA	Streptococcus pneumoniae D39	99.779	100	0.998
radA	Streptococcus pneumoniae R6	99.779	100	0.998
radA	Streptococcus pneumoniae TIGR4	99.779	100	0.998
radA	Streptococcus mitis NCTC 12261	99.338	100	0.993
radA	Streptococcus mitis SK321	99.338	100	0.993
radA	Bacillus subtilis subsp. subtilis str. 168	63.355	100	0.634