Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   R4700_RS03945 Genome accession   NZ_CP137112
Coordinates   762811..764067 (-) Length   418 a.a.
NCBI ID   WP_000642709.1    Uniprot ID   A0A0E8AGF5
Organism   Streptococcus pneumoniae strain 02H2025     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 757811..769067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4700_RS03920 - 757881..758087 (-) 207 WP_000366088.1 hypothetical protein -
  R4700_RS03925 - 758074..758235 (-) 162 WP_001055999.1 helix-turn-helix domain-containing protein -
  R4700_RS03930 lytA 758581..759537 (-) 957 WP_001862690.1 N-acetylmuramoyl-L-alanine amidase LytA -
  R4700_RS03935 - 759913..761283 (-) 1371 WP_001036282.1 MATE family efflux transporter -
  R4700_RS03940 recA 761590..762756 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R4700_RS03945 cinA 762811..764067 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  R4700_RS03950 brpA 764152..765168 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4700_RS03955 - 765176..765694 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R4700_RS03960 tsaE 765684..766127 (-) 444 WP_000275589.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4700_RS03965 comM 766213..766833 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R4700_RS03970 - 767216..768079 (-) 864 Protein_768 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45075.48 Da        Isoelectric Point: 4.6064

>NTDB_id=896017 R4700_RS03945 WP_000642709.1 762811..764067(-) (cinA) [Streptococcus pneumoniae strain 02H2025]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=896017 R4700_RS03945 WP_000642709.1 762811..764067(-) (cinA) [Streptococcus pneumoniae strain 02H2025]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACCGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E8AGF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae Rx1

99.282

100

0.993
  cinA Streptococcus pneumoniae R6

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.043

100

0.99
  cinA Streptococcus mitis SK321

94.019

100

0.94
  cinA Streptococcus mitis NCTC 12261

93.78

100

0.938
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455