Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4712_RS06270 Genome accession   NZ_CP137110
Coordinates   1243045..1243347 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2041     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1238045..1248347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS06240 - 1238802..1239860 (+) 1059 WP_044812807.1 zinc-dependent alcohol dehydrogenase family protein -
  R4712_RS06245 - 1240011..1240376 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4712_RS06250 comGA/cglA/cilD 1240452..1241393 (+) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  R4712_RS06255 comGB/cglB 1241341..1242357 (+) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4712_RS06260 comGC/cglC 1242359..1242685 (+) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  R4712_RS06265 comGD/cglD 1242678..1243082 (+) 405 WP_288176807.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4712_RS06270 comGE/cglE 1243045..1243347 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4712_RS06275 comGF/cglF 1243310..1243771 (+) 462 WP_001864569.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4712_RS06280 comGG/cglG 1243749..1244162 (+) 414 WP_001864570.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4712_RS06285 - 1244299..1244893 (+) 595 Protein_1230 class I SAM-dependent methyltransferase -
  R4712_RS06290 comYH 1244954..1245907 (+) 954 WP_001866278.1 class I SAM-dependent methyltransferase Machinery gene
  R4712_RS06295 - 1245958..1247148 (+) 1191 WP_000167766.1 acetate kinase -
  R4712_RS06300 - 1247149..1247280 (+) 132 WP_000768904.1 hypothetical protein -
  R4712_RS06305 rnpA 1247297..1247668 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=895876 R4712_RS06270 WP_000413382.1 1243045..1243347(+) (comGE/cglE) [Streptococcus pneumoniae strain 16H2041]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=895876 R4712_RS06270 WP_000413382.1 1243045..1243347(+) (comGE/cglE) [Streptococcus pneumoniae strain 16H2041]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4