Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4712_RS06290 Genome accession   NZ_CP137110
Coordinates   1244954..1245907 (+) Length   317 a.a.
NCBI ID   WP_001866278.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2041     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1239954..1250907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS06245 - 1240011..1240376 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4712_RS06250 comGA/cglA/cilD 1240452..1241393 (+) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  R4712_RS06255 comGB/cglB 1241341..1242357 (+) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4712_RS06260 comGC/cglC 1242359..1242685 (+) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  R4712_RS06265 comGD/cglD 1242678..1243082 (+) 405 WP_288176807.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4712_RS06270 comGE/cglE 1243045..1243347 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4712_RS06275 comGF/cglF 1243310..1243771 (+) 462 WP_001864569.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4712_RS06280 comGG/cglG 1243749..1244162 (+) 414 WP_001864570.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4712_RS06285 - 1244299..1244893 (+) 595 Protein_1230 class I SAM-dependent methyltransferase -
  R4712_RS06290 comYH 1244954..1245907 (+) 954 WP_001866278.1 class I SAM-dependent methyltransferase Machinery gene
  R4712_RS06295 - 1245958..1247148 (+) 1191 WP_000167766.1 acetate kinase -
  R4712_RS06300 - 1247149..1247280 (+) 132 WP_000768904.1 hypothetical protein -
  R4712_RS06305 rnpA 1247297..1247668 (+) 372 WP_000739246.1 ribonuclease P protein component -
  R4712_RS06310 - 1247643..1248467 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  R4712_RS06315 jag 1248486..1249472 (+) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  R4712_RS06320 - 1249523..1250146 (+) 624 WP_000932660.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35699.89 Da        Isoelectric Point: 4.2434

>NTDB_id=895879 R4712_RS06290 WP_001866278.1 1244954..1245907(+) (comYH) [Streptococcus pneumoniae strain 16H2041]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895879 R4712_RS06290 WP_001866278.1 1244954..1245907(+) (comYH) [Streptococcus pneumoniae strain 16H2041]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539