Detailed information NTG0895878

Bioinformatically predicted

Overview

• Name: comGG/cglG
• Type: Machinery gene
• Locus tag: R4712_RS06280
• Genome accession: NZ_CP137110
• Coordinates: 1243749..1244162 (+)
• Length: 137 a.a.
• NCBI ID: WP_001864570.1
• Uniprot ID: A0A0T8D4A3
• Organism: Streptococcus pneumoniae strain 16H2041
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1238749..1249162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4712_RS06240	-	1238802..1239860 (+)	1059	WP_044812807.1	zinc-dependent alcohol dehydrogenase family protein	-
R4712_RS06245	-	1240011..1240376 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4712_RS06250	comGA/cglA/cilD	1240452..1241393 (+)	942	WP_016398028.1	competence type IV pilus ATPase ComGA	Machinery gene
R4712_RS06255	comGB/cglB	1241341..1242357 (+)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4712_RS06260	comGC/cglC	1242359..1242685 (+)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
R4712_RS06265	comGD/cglD	1242678..1243082 (+)	405	WP_288176807.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4712_RS06270	comGE/cglE	1243045..1243347 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4712_RS06275	comGF/cglF	1243310..1243771 (+)	462	WP_001864569.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4712_RS06280	comGG/cglG	1243749..1244162 (+)	414	WP_001864570.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4712_RS06285	-	1244299..1244893 (+)	595	Protein_1230	class I SAM-dependent methyltransferase	-
R4712_RS06290	comYH	1244954..1245907 (+)	954	WP_001866278.1	class I SAM-dependent methyltransferase	Machinery gene
R4712_RS06295	-	1245958..1247148 (+)	1191	WP_000167766.1	acetate kinase	-
R4712_RS06300	-	1247149..1247280 (+)	132	WP_000768904.1	hypothetical protein	-
R4712_RS06305	rnpA	1247297..1247668 (+)	372	WP_000739246.1	ribonuclease P protein component	-
R4712_RS06310	-	1247643..1248467 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 137 a.a.
• Molecular weight: 15906.36 Da
• Isoelectric Point: 10.2476

>NTDB_id=895878 R4712_RS06280 WP_001864570.1 1243749..1244162(+) (comGG/cglG) [Streptococcus pneumoniae strain 16H2041]
MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQIAHYQDYALNKEKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKK
TSLVTTVRTSKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide

• Length: 414 bp

>NTDB_id=895878 R4712_RS06280 WP_001864570.1 1243749..1244162(+) (comGG/cglG) [Streptococcus pneumoniae strain 16H2041]
GTGTGGAAAAAGAAGAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATGGCAGCTATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAATCGCCCACTATCAAGACTATGCTTTAAATAAAGAAAAATTGGTTGCTTTTGCCATGGCTA
AACGAACCAAGGATAAAGCCGAGCAAGAAAGTGGGGAACAGGTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACAAGCTTGGTGACGACTGTTCGTACGTCTAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCCTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0T8D4A3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGG/cglG	Streptococcus mitis SK321	85.401	100	0.854
comGG/cglG	Streptococcus pneumoniae Rx1	94.017	85.401	0.803
comGG/cglG	Streptococcus pneumoniae D39	94.017	85.401	0.803
comGG/cglG	Streptococcus pneumoniae R6	94.017	85.401	0.803
comGG/cglG	Streptococcus pneumoniae TIGR4	94.017	85.401	0.803
comGG/cglG	Streptococcus mitis NCTC 12261	90.083	88.321	0.796
comYG	Streptococcus mutans UA140	38.806	97.81	0.38
comYG	Streptococcus mutans UA159	38.806	97.81	0.38