NTDB

Overview

Name	comGF/cglF	Type	Machinery gene
Locus tag	R4712_RS06275	Genome accession	NZ_CP137110
Coordinates	1243310..1243771 (+)	Length	153 a.a.
NCBI ID	WP_001864569.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain 16H2041
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1238310..1248771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4712_RS06240	-	1238802..1239860 (+)	1059	WP_044812807.1	zinc-dependent alcohol dehydrogenase family protein	-
R4712_RS06245	-	1240011..1240376 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4712_RS06250	comGA/cglA/cilD	1240452..1241393 (+)	942	WP_016398028.1	competence type IV pilus ATPase ComGA	Machinery gene
R4712_RS06255	comGB/cglB	1241341..1242357 (+)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4712_RS06260	comGC/cglC	1242359..1242685 (+)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
R4712_RS06265	comGD/cglD	1242678..1243082 (+)	405	WP_288176807.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4712_RS06270	comGE/cglE	1243045..1243347 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4712_RS06275	comGF/cglF	1243310..1243771 (+)	462	WP_001864569.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4712_RS06280	comGG/cglG	1243749..1244162 (+)	414	WP_001864570.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4712_RS06285	-	1244299..1244893 (+)	595	Protein_1230	class I SAM-dependent methyltransferase	-
R4712_RS06290	comYH	1244954..1245907 (+)	954	WP_001866278.1	class I SAM-dependent methyltransferase	Machinery gene
R4712_RS06295	-	1245958..1247148 (+)	1191	WP_000167766.1	acetate kinase	-
R4712_RS06300	-	1247149..1247280 (+)	132	WP_000768904.1	hypothetical protein	-
R4712_RS06305	rnpA	1247297..1247668 (+)	372	WP_000739246.1	ribonuclease P protein component	-
R4712_RS06310	-	1247643..1248467 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

Download Length: 153 a.a. Molecular weight: 17814.34 Da Isoelectric Point: 6.9595

                                >NTDB_id=895877 R4712_RS06275 WP_001864569.1 1243310..1243771(+) (comGF/cglF) [Streptococcus pneumoniae strain 16H2041]

MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRCQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN

RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEES

Nucleotide

Download Length: 462 bp

                                >NTDB_id=895877 R4712_RS06275 WP_001864569.1 1243310..1243771(+) (comGF/cglF) [Streptococcus pneumoniae strain 16H2041]

ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT

TGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTGCCAGCAACAAAGCG

AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT

CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG

TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCCGCACAGATTACAGAGGACAATCAACTGGTGCGCTTTCGTT

TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(47-141)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915

Detailed information NTG0895877