Detailed information NTG0895643

Bioinformatically predicted

Overview

• Name: comGB/cglB
• Type: Machinery gene
• Locus tag: R4711_RS06575
• Genome accession: NZ_CP137107
• Coordinates: 1302434..1303450 (+)
• Length: 338 a.a.
• NCBI ID: WP_077141332.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1297434..1308450

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS06555	nagA	1298581..1299732 (+)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
R4711_RS06560	-	1299895..1300953 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4711_RS06565	-	1301104..1301469 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4711_RS06570	comGA/cglA/cilD	1301545..1302486 (+)	942	WP_000249550.1	competence type IV pilus ATPase ComGA	Machinery gene
R4711_RS06575	comGB/cglB	1302434..1303450 (+)	1017	WP_077141332.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4711_RS06580	comGC/cglC	1303452..1303778 (+)	327	WP_000738623.1	comG operon protein ComGC	Machinery gene
R4711_RS06585	comGD/cglD	1303771..1304175 (+)	405	WP_000588002.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4711_RS06590	comGE/cglE	1304138..1304440 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4711_RS06595	comGF/cglF	1304403..1304864 (+)	462	WP_000250529.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4711_RS06600	comGG/cglG	1304842..1305255 (+)	414	WP_000265617.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4711_RS06605	-	1305392..1305979 (+)	588	Protein_1291	class I SAM-dependent methyltransferase	-
R4711_RS06610	comYH	1306040..1306993 (+)	954	WP_000345086.1	class I SAM-dependent methyltransferase	Machinery gene
R4711_RS06615	-	1307044..1308234 (+)	1191	WP_000167755.1	acetate kinase	-

Sequence

Protein

• Length: 338 a.a.
• Molecular weight: 38466.48 Da
• Isoelectric Point: 9.6162

>NTDB_id=895643 R4711_RS06575 WP_077141332.1 1302434..1303450(+) (comGB/cglB) [Streptococcus pneumoniae strain 15H4024]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide

• Length: 1017 bp

>NTDB_id=895643 R4711_RS06575 WP_077141332.1 1302434..1303450(+) (comGB/cglB) [Streptococcus pneumoniae strain 15H4024]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTTATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (24-141)

• Type II secretion system (T2SS), protein F (T2SSF) (209-329)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB/cglB	Streptococcus pneumoniae Rx1	98.817	100	0.988
comGB/cglB	Streptococcus pneumoniae D39	98.817	100	0.988
comGB/cglB	Streptococcus pneumoniae R6	98.817	100	0.988
comGB/cglB	Streptococcus pneumoniae TIGR4	98.817	100	0.988
comGB/cglB	Streptococcus mitis SK321	95.266	100	0.953
comGB/cglB	Streptococcus mitis NCTC 12261	94.379	100	0.944
comYB	Streptococcus gordonii str. Challis substr. CH1	70.833	99.408	0.704
comYB	Streptococcus mutans UA140	58.176	94.083	0.547
comYB	Streptococcus mutans UA159	58.176	94.083	0.547
comGB	Lactococcus lactis subsp. cremoris KW2	50.898	98.817	0.503