Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   R4711_RS06580 Genome accession   NZ_CP137107
Coordinates   1303452..1303778 (+) Length   108 a.a.
NCBI ID   WP_000738623.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1298452..1308778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS06555 nagA 1298581..1299732 (+) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  R4711_RS06560 - 1299895..1300953 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R4711_RS06565 - 1301104..1301469 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4711_RS06570 comGA/cglA/cilD 1301545..1302486 (+) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  R4711_RS06575 comGB/cglB 1302434..1303450 (+) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4711_RS06580 comGC/cglC 1303452..1303778 (+) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  R4711_RS06585 comGD/cglD 1303771..1304175 (+) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4711_RS06590 comGE/cglE 1304138..1304440 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4711_RS06595 comGF/cglF 1304403..1304864 (+) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4711_RS06600 comGG/cglG 1304842..1305255 (+) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4711_RS06605 - 1305392..1305979 (+) 588 Protein_1291 class I SAM-dependent methyltransferase -
  R4711_RS06610 comYH 1306040..1306993 (+) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  R4711_RS06615 - 1307044..1308234 (+) 1191 WP_000167755.1 acetate kinase -
  R4711_RS06620 rnpA 1308382..1308753 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12187.38 Da        Isoelectric Point: 10.0523

>NTDB_id=895644 R4711_RS06580 WP_000738623.1 1303452..1303778(+) (comGC/cglC) [Streptococcus pneumoniae strain 15H4024]
MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=895644 R4711_RS06580 WP_000738623.1 1303452..1303778(+) (comGC/cglC) [Streptococcus pneumoniae strain 15H4024]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGATTGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

97.222

100

0.972

  comGC/cglC Streptococcus pneumoniae D39

97.222

100

0.972

  comGC/cglC Streptococcus pneumoniae R6

97.222

100

0.972

  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963

  comGC/cglC Streptococcus mitis SK321

93.519

100

0.935

  comGC/cglC Streptococcus mitis NCTC 12261

92.157

94.444

0.87

  comYC Streptococcus gordonii str. Challis substr. CH1

71.875

88.889

0.639

  comYC Streptococcus mutans UA159

64.706

94.444

0.611

  comYC Streptococcus mutans UA140

64.706

94.444

0.611

  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528

  comYC Streptococcus suis isolate S10

69.136

75

0.519

  comGC Staphylococcus aureus MW2

51.163

79.63

0.407

  comGC Staphylococcus aureus N315

51.163

79.63

0.407

  comGC Latilactobacillus sakei subsp. sakei 23K

46.512

79.63

0.37