Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ABC967_RS05195 Genome accession   NZ_CP155059
Coordinates   1085457..1087238 (+) Length   593 a.a.
NCBI ID   WP_000390537.1    Uniprot ID   -
Organism   Staphylococcus aureus strain CC133-MSSA     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1080457..1092238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC967_RS05175 (ABC967_05175) polX 1080576..1082288 (+) 1713 WP_109183072.1 DNA polymerase/3'-5' exonuclease PolX -
  ABC967_RS05180 (ABC967_05180) mutS/mutS2 1082298..1084646 (+) 2349 WP_001249271.1 endonuclease MutS2 Machinery gene
  ABC967_RS05185 (ABC967_05185) trxA 1084819..1085133 (+) 315 WP_001018928.1 thioredoxin -
  ABC967_RS05190 (ABC967_05190) - 1085196..1085291 (-) 96 WP_041204276.1 hypothetical protein -
  ABC967_RS05195 (ABC967_05195) uvrC 1085457..1087238 (+) 1782 WP_000390537.1 excinuclease ABC subunit UvrC Machinery gene
  ABC967_RS05200 (ABC967_05200) - 1087562..1088176 (+) 615 WP_000079321.1 succinate dehydrogenase cytochrome b558 subunit -
  ABC967_RS05205 (ABC967_05205) sdhA 1088228..1089994 (+) 1767 WP_000818283.1 succinate dehydrogenase flavoprotein subunit -
  ABC967_RS05210 (ABC967_05210) sdhB 1089994..1090809 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  ABC967_RS05215 (ABC967_05215) racE 1091048..1091848 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68627.35 Da        Isoelectric Point: 9.8215

>NTDB_id=895645 ABC967_RS05195 WP_000390537.1 1085457..1087238(+) (uvrC) [Staphylococcus aureus strain CC133-MSSA]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYNVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGGKRKTLLLRTF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=895645 ABC967_RS05195 WP_000390537.1 1085457..1087238(+) (uvrC) [Staphylococcus aureus strain CC133-MSSA]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCTAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCAA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATAACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGAGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGTTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATCCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGATGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCGGATTTAATTA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAAAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATCCTTGATGATATAGATGGTATCGGTGGCAAACGTAAAACATTATTATTGCGTACATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae R6

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae D39

57.436

98.651

0.567