Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD/cglD   Type   Machinery gene
Locus tag   R4711_RS06585 Genome accession   NZ_CP137107
Coordinates   1303771..1304175 (+) Length   134 a.a.
NCBI ID   WP_000588002.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1298771..1309175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS06560 - 1299895..1300953 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R4711_RS06565 - 1301104..1301469 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4711_RS06570 comGA/cglA/cilD 1301545..1302486 (+) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  R4711_RS06575 comGB/cglB 1302434..1303450 (+) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4711_RS06580 comGC/cglC 1303452..1303778 (+) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  R4711_RS06585 comGD/cglD 1303771..1304175 (+) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4711_RS06590 comGE/cglE 1304138..1304440 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4711_RS06595 comGF/cglF 1304403..1304864 (+) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4711_RS06600 comGG/cglG 1304842..1305255 (+) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4711_RS06605 - 1305392..1305979 (+) 588 Protein_1291 class I SAM-dependent methyltransferase -
  R4711_RS06610 comYH 1306040..1306993 (+) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  R4711_RS06615 - 1307044..1308234 (+) 1191 WP_000167755.1 acetate kinase -
  R4711_RS06620 rnpA 1308382..1308753 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 14667.82 Da        Isoelectric Point: 10.2164

>NTDB_id=895645 R4711_RS06585 WP_000588002.1 1303771..1304175(+) (comGD/cglD) [Streptococcus pneumoniae strain 15H4024]
MIKAFTMLESLLALSLVSILALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTV
PKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN

Nucleotide


Download         Length: 405 bp        

>NTDB_id=895645 R4711_RS06585 WP_000588002.1 1303771..1304175(+) (comGD/cglD) [Streptococcus pneumoniae strain 15H4024]
ATGATTAAGGCCTTTACCATGCTGGAAAGTCTCTTGGCTTTGAGTCTTGTGAGTATCCTTGCCTTGGGCTTGTCCGGCTC
TGTTCAGTCCACTTTTGCGGCAGTAGAGGAACAGATTTTCTTTATGGAGTTTGAAGAACTCTATCGGGAAACCCAAAAAC
GCAGTGTAGCCAGTCAGCAAAAGACTAATCTAAATTTAGATGGGCAGACGCTTAGCAATGGCAGTCAAAAGTTGACAGTT
CCTAAAGGAATTCAGGCACCATCAGGCCAAAGTATTACATTTGACCGAGCTGGGGGCAATTCGTCCCTGGCTAAGGTTGA
ATTTCAGACCAGTAAAGGAGCGATTCGCTATCAATTATATCTAGGAAATGGAAAAATTAAACGCATTAAGGAAACAAAAA
ATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus pneumoniae TIGR4

96.269

100

0.963
  comGD/cglD Streptococcus pneumoniae Rx1

95.522

100

0.955
  comGD/cglD Streptococcus pneumoniae D39

95.522

100

0.955
  comGD/cglD Streptococcus pneumoniae R6

95.522

100

0.955
  comGD/cglD Streptococcus mitis NCTC 12261

95.489

99.254

0.948
  comGD/cglD Streptococcus mitis SK321

94.776

100

0.948
  comYD Streptococcus gordonii str. Challis substr. CH1

57.48

94.776

0.545
  comYD Streptococcus mutans UA140

49.219

95.522

0.47
  comYD Streptococcus mutans UA159

49.219

95.522

0.47