Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4711_RS06590 Genome accession   NZ_CP137107
Coordinates   1304138..1304440 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1299138..1309440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS06560 - 1299895..1300953 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R4711_RS06565 - 1301104..1301469 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4711_RS06570 comGA/cglA/cilD 1301545..1302486 (+) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  R4711_RS06575 comGB/cglB 1302434..1303450 (+) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4711_RS06580 comGC/cglC 1303452..1303778 (+) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  R4711_RS06585 comGD/cglD 1303771..1304175 (+) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4711_RS06590 comGE/cglE 1304138..1304440 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4711_RS06595 comGF/cglF 1304403..1304864 (+) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4711_RS06600 comGG/cglG 1304842..1305255 (+) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4711_RS06605 - 1305392..1305979 (+) 588 Protein_1291 class I SAM-dependent methyltransferase -
  R4711_RS06610 comYH 1306040..1306993 (+) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  R4711_RS06615 - 1307044..1308234 (+) 1191 WP_000167755.1 acetate kinase -
  R4711_RS06620 rnpA 1308382..1308753 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=895646 R4711_RS06590 WP_000413382.1 1304138..1304440(+) (comGE/cglE) [Streptococcus pneumoniae strain 15H4024]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=895646 R4711_RS06590 WP_000413382.1 1304138..1304440(+) (comGE/cglE) [Streptococcus pneumoniae strain 15H4024]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4