Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4711_RS06610 Genome accession   NZ_CP137107
Coordinates   1306040..1306993 (+) Length   317 a.a.
NCBI ID   WP_000345086.1    Uniprot ID   A0A064C057
Organism   Streptococcus pneumoniae strain 15H4024     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1301040..1311993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS06565 - 1301104..1301469 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4711_RS06570 comGA/cglA/cilD 1301545..1302486 (+) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  R4711_RS06575 comGB/cglB 1302434..1303450 (+) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4711_RS06580 comGC/cglC 1303452..1303778 (+) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  R4711_RS06585 comGD/cglD 1303771..1304175 (+) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4711_RS06590 comGE/cglE 1304138..1304440 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4711_RS06595 comGF/cglF 1304403..1304864 (+) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4711_RS06600 comGG/cglG 1304842..1305255 (+) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4711_RS06605 - 1305392..1305979 (+) 588 Protein_1291 class I SAM-dependent methyltransferase -
  R4711_RS06610 comYH 1306040..1306993 (+) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  R4711_RS06615 - 1307044..1308234 (+) 1191 WP_000167755.1 acetate kinase -
  R4711_RS06620 rnpA 1308382..1308753 (+) 372 WP_000739246.1 ribonuclease P protein component -
  R4711_RS06625 - 1308728..1309552 (+) 825 WP_201417363.1 membrane protein insertase YidC -
  R4711_RS06630 jag 1309571..1310557 (+) 987 WP_050263793.1 RNA-binding cell elongation regulator Jag/EloR -
  R4711_RS06635 - 1310608..1311231 (+) 624 WP_000932660.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35676.86 Da        Isoelectric Point: 4.2270

>NTDB_id=895649 R4711_RS06610 WP_000345086.1 1306040..1306993(+) (comYH) [Streptococcus pneumoniae strain 15H4024]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895649 R4711_RS06610 WP_000345086.1 1306040..1306993(+) (comYH) [Streptococcus pneumoniae strain 15H4024]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C057

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536