Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   R4703_RS04000 Genome accession   NZ_CP137100
Coordinates   735891..737147 (-) Length   418 a.a.
NCBI ID   WP_000642704.1    Uniprot ID   C1CTH7
Organism   Streptococcus pneumoniae strain LYP     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 730891..742147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS03975 - 730948..731154 (-) 207 WP_000366087.1 hypothetical protein -
  R4703_RS03980 - 731141..731302 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  R4703_RS03985 lytA 731661..732617 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  R4703_RS03990 - 732993..734363 (-) 1371 WP_001036271.1 MATE family efflux transporter -
  R4703_RS03995 recA 734670..735836 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  R4703_RS04000 cinA 735891..737147 (-) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene
  R4703_RS04005 brpA 737232..738248 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4703_RS04010 - 738256..738774 (-) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  R4703_RS04015 tsaE 738764..739207 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4703_RS04020 comM 739293..739913 (-) 621 WP_000839909.1 hypothetical protein Regulator
  R4703_RS04025 - 740296..741159 (-) 864 WP_001093627.1 helix-turn-helix domain-containing protein -
  R4703_RS04030 - 741347..741516 (+) 170 Protein_781 PhrA family quorum-sensing system peptide -
  R4703_RS04035 - 741831..742127 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45089.42 Da        Isoelectric Point: 4.5211

>NTDB_id=895089 R4703_RS04000 WP_000642704.1 735891..737147(-) (cinA) [Streptococcus pneumoniae strain LYP]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=895089 R4703_RS04000 WP_000642704.1 735891..737147(-) (cinA) [Streptococcus pneumoniae strain LYP]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAACAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTGAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CTH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae Rx1

99.522

100

0.995
  cinA Streptococcus pneumoniae R6

99.522

100

0.995
  cinA Streptococcus pneumoniae TIGR4

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.282

100

0.993
  cinA Streptococcus mitis SK321

93.301

100

0.933
  cinA Streptococcus mitis NCTC 12261

93.062

100

0.931
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455