Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R4703_RS04020 Genome accession   NZ_CP137100
Coordinates   739293..739913 (-) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain LYP     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 734293..744913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS03995 recA 734670..735836 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  R4703_RS04000 cinA 735891..737147 (-) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene
  R4703_RS04005 brpA 737232..738248 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4703_RS04010 - 738256..738774 (-) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  R4703_RS04015 tsaE 738764..739207 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4703_RS04020 comM 739293..739913 (-) 621 WP_000839909.1 hypothetical protein Regulator
  R4703_RS04025 - 740296..741159 (-) 864 WP_001093627.1 helix-turn-helix domain-containing protein -
  R4703_RS04030 - 741347..741516 (+) 170 Protein_781 PhrA family quorum-sensing system peptide -
  R4703_RS04035 - 741831..742127 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  R4703_RS04040 - 742230..744245 (+) 2016 WP_000732372.1 DUF1430 domain-containing protein -
  R4703_RS04045 - 744247..744879 (+) 633 WP_000571422.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=895090 R4703_RS04020 WP_000839909.1 739293..739913(-) (comM) [Streptococcus pneumoniae strain LYP]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=895090 R4703_RS04020 WP_000839909.1 739293..739913(-) (comM) [Streptococcus pneumoniae strain LYP]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364