Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   R4535_RS10690 Genome accession   NZ_CP137091
Coordinates   2386563..2387789 (+) Length   408 a.a.
NCBI ID   WP_000648510.1    Uniprot ID   -
Organism   Vibrio cholerae strain DL4211     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2381563..2392789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4535_RS10670 (R4535_10645) ampD 2382445..2382990 (-) 546 WP_076025708.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  R4535_RS10675 (R4535_10650) nadC 2383286..2384176 (+) 891 WP_000665278.1 carboxylating nicotinate-nucleotide diphosphorylase -
  R4535_RS10680 (R4535_10655) - 2384421..2384825 (+) 405 WP_057551631.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  R4535_RS10685 (R4535_10660) pilB 2384832..2386520 (+) 1689 WP_076025706.1 type IV-A pilus assembly ATPase PilB Machinery gene
  R4535_RS10690 (R4535_10665) pilC 2386563..2387789 (+) 1227 WP_000648510.1 type II secretion system F family protein Machinery gene
  R4535_RS10695 (R4535_10670) pilD 2387847..2388722 (+) 876 WP_076025705.1 A24 family peptidase Machinery gene
  R4535_RS10700 (R4535_10675) coaE 2388719..2389327 (+) 609 WP_175597578.1 dephospho-CoA kinase -
  R4535_RS10705 (R4535_10680) zapD 2389359..2390099 (+) 741 WP_000207194.1 cell division protein ZapD -
  R4535_RS10710 (R4535_10685) yacG 2390257..2390454 (+) 198 WP_000162865.1 DNA gyrase inhibitor YacG -
  R4535_RS10715 (R4535_10690) parC 2390503..2392788 (-) 2286 WP_207807156.1 DNA topoisomerase IV subunit A -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45120.41 Da        Isoelectric Point: 10.3424

>NTDB_id=894966 R4535_RS10690 WP_000648510.1 2386563..2387789(+) (pilC) [Vibrio cholerae strain DL4211]
MKATQTLPLKNYRWKGINSNGKKVSGQMLAISEIEVRDKLKDQHIQIKKLKKGSVSLLARLTHRVKSKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVQAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFETAINEVYRDTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=894966 R4535_RS10690 WP_000648510.1 2386563..2387789(+) (pilC) [Vibrio cholerae strain DL4211]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAACAGCAACGGCAAAAAAGTTTCCGGTCA
GATGCTCGCCATCTCCGAAATCGAGGTGCGCGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTCAAAAAAGGCA
GTGTCTCTTTATTGGCGCGCCTAACCCATCGCGTGAAAAGCAAAGACATCACGATTTTGACTCGGCAGTTGGCGACCATG
CTCACCACGGGCGTACCCATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATCACCAAAAGTGTGGAAGCGGGCACGCCGCTTTCCAAGGCGATGCGCACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGACTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAGGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAACAGCTACGCGCCAAGGTGATCAAAGCGCTCATCTACCCCAGCATGGTGGTGTTGGTTGCGCTCGGAGTTTC
CTACTTAATGCTCACCATGGTCATCCCAGAATTTGAAAGCATGTTTAAAGGCTTTGGTGCTGAACTGCCTTGGTTTACGC
AGCAAGTGCTGAAACTCTCACACTGGGTGCAGGCTTACAGTTTATGGGCATTTATCGCCATCGCAGCAGCCATTTTTGGC
TTGAAAGCGCTGCGTAAAAACTCTTTCCAGATCCGTTTAAAAACCAGCCGCTTAGGGCTGAAATTTCCGATTATTGGTAA
TGTGCTCGCTAAGGCTTCCATCGCCAAATTCAGCCGCACCCTCGCCACCAGCTTTGCCGCGGGGATACCGATCCTCGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAACCGCGATTAATGAGGTGTACCGCGATACCGCTGCG
GGTATGCCGATGTACATTGCCATGCGCAATACCGACGCTTTTCCGGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCAGGGCAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACAGTCGATAACTTGG
GCAAGATTCTTGAACCACTGATCATCGTGTTTCTTGGGACGGTCGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.755

100

0.998
  pilC Vibrio campbellii strain DS40M4

73.75

98.039

0.723
  pilC Acinetobacter baumannii D1279779

42.647

100

0.426
  pilC Acinetobacter baylyi ADP1

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.211

97.549

0.412
  pilC Pseudomonas stutzeri DSM 10701

42.172

97.059

0.409
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilG Neisseria meningitidis 44/76-A

40.547

98.529

0.4