Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   F6I35_RS01325 Genome accession   NZ_CP136160
Coordinates   229341..230282 (+) Length   313 a.a.
NCBI ID   WP_024053130.1    Uniprot ID   -
Organism   Streptococcus anginosus strain UMB8616     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 224341..235282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS01300 (F6I35_0001300) - 224654..225853 (+) 1200 WP_024053134.1 phosphoglycerate kinase -
  F6I35_RS01305 (F6I35_0001305) - 226368..226898 (+) 531 WP_070241503.1 FUSC family protein -
  F6I35_RS01310 (F6I35_0001310) - 226975..227334 (+) 360 WP_003070793.1 MerR family transcriptional regulator -
  F6I35_RS01315 (F6I35_0001315) glnA 227372..228718 (+) 1347 WP_024053132.1 type I glutamate--ammonia ligase -
  F6I35_RS01320 (F6I35_0001320) - 228906..229271 (+) 366 WP_024053131.1 DUF1033 family protein -
  F6I35_RS01325 (F6I35_0001325) comYA 229341..230282 (+) 942 WP_024053130.1 competence type IV pilus ATPase ComGA Machinery gene
  F6I35_RS01330 (F6I35_0001330) comYB 230224..231246 (+) 1023 WP_171021869.1 competence type IV pilus assembly protein ComGB Machinery gene
  F6I35_RS01335 (F6I35_0001335) - 231310..232755 (-) 1446 WP_150867047.1 recombinase family protein -
  F6I35_RS01340 (F6I35_0001340) - 232903..233556 (-) 654 WP_150867045.1 SHOCT domain-containing protein -
  F6I35_RS01345 (F6I35_0001345) - 233571..234374 (-) 804 WP_143876462.1 S24 family peptidase -
  F6I35_RS01350 (F6I35_0001350) - 234544..234780 (+) 237 WP_191621614.1 DUF739 family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35929.17 Da        Isoelectric Point: 6.2451

>NTDB_id=888930 F6I35_RS01325 WP_024053130.1 229341..230282(+) (comYA) [Streptococcus anginosus strain UMB8616]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEEMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFADQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGMTVFSTIHAKSVRGVY
ERLLELGVTEAELKVVLQGICYQRLIAKGGIVDFVSEKYQEHEPIDWNRQIDQLHAAGHINLEQAEAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=888930 F6I35_RS01325 WP_024053130.1 229341..230282(+) (comYA) [Streptococcus anginosus strain UMB8616]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGATGGCAGCAG
TAATTAGTCATTTTAAGTTTACTGCTGGGATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGTTCTTGTGATTATCAA
TATGGTGATAAGAAAACGTCATTACGACTATCAACAGTAGGGGATTATCGTGGATACGAAAGTCTGGTGATTCGTTTATT
GCATGATGAAGAGGCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAACGCTTCAAACAACGAGGGCTTT
ATCTTTTTTCGGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCAGAGACAG
CAAGGGCAGTTGTTCGAGCTAGCTTAACGGGAATGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCCGAGCTGAAAGTTGTCTTACAAGGGATTTGTTACCAACGCTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAGAAGTATCAAGAACACGAGCCAATCGATTGGAATAGGCAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAGCAGGCAGAAGCGGAAAAAATTATCCACAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

82.903

99.042

0.821
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

44.697

84.345

0.377