NTDB

Overview

Name	comYB	Type	Machinery gene
Locus tag	F6I35_RS01330	Genome accession	NZ_CP136160
Coordinates	230224..231246 (+)	Length	340 a.a.
NCBI ID	WP_171021869.1	Uniprot ID	-
Organism	Streptococcus anginosus strain UMB8616
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 225224..236246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6I35_RS01305 (F6I35_0001305)	-	226368..226898 (+)	531	WP_070241503.1	FUSC family protein	-
F6I35_RS01310 (F6I35_0001310)	-	226975..227334 (+)	360	WP_003070793.1	MerR family transcriptional regulator	-
F6I35_RS01315 (F6I35_0001315)	glnA	227372..228718 (+)	1347	WP_024053132.1	type I glutamate--ammonia ligase	-
F6I35_RS01320 (F6I35_0001320)	-	228906..229271 (+)	366	WP_024053131.1	DUF1033 family protein	-
F6I35_RS01325 (F6I35_0001325)	comYA	229341..230282 (+)	942	WP_024053130.1	competence type IV pilus ATPase ComGA	Machinery gene
F6I35_RS01330 (F6I35_0001330)	comYB	230224..231246 (+)	1023	WP_171021869.1	competence type IV pilus assembly protein ComGB	Machinery gene
F6I35_RS01335 (F6I35_0001335)	-	231310..232755 (-)	1446	WP_150867047.1	recombinase family protein	-
F6I35_RS01340 (F6I35_0001340)	-	232903..233556 (-)	654	WP_150867045.1	SHOCT domain-containing protein	-
F6I35_RS01345 (F6I35_0001345)	-	233571..234374 (-)	804	WP_143876462.1	S24 family peptidase	-
F6I35_RS01350 (F6I35_0001350)	-	234544..234780 (+)	237	WP_191621614.1	DUF739 family protein	-
F6I35_RS01355 (F6I35_0001355)	-	234793..235524 (+)	732	WP_191621613.1	phage antirepressor KilAC domain-containing protein	-
F6I35_RS01360 (F6I35_0001360)	-	235589..235747 (+)	159	WP_181877640.1	BOW99_gp33 family protein	-
F6I35_RS01365 (F6I35_0001365)	-	235757..236119 (+)	363	WP_115283070.1	helix-turn-helix domain-containing protein	-
F6I35_RS10800	-	236123..236206 (-)	84	WP_143876768.1	pentapeptide repeat-containing protein	-

Sequence

Protein

Download Length: 340 a.a. Molecular weight: 39170.30 Da Isoelectric Point: 9.5495

                                >NTDB_id=888931 F6I35_RS01330 WP_171021869.1 230224..231246(+) (comYB) [Streptococcus anginosus strain UMB8616]

MQQDISILSRQKRKKLSTVRQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEEVYVDRMKEELSTGKPFSDIMASLGFSD

NVVTQLSLAELHGNLSLSLSKIEEYLENISKIKKKLVEVATYPFILFVFLIFIMLGLRNYLLPQLDRQNIATQIISNLPQ

LFLGSLGVVFVLLAIGFYWFQKSSKIAVFRLLARLPFLGAFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ

EIGKDLEVALQNGQEFSQRVKTYPFFKKELGLMIEYGEVKSKLGCELEVYAQKTWETFFKRVHQAMNVIQPLVFVFVALM

IVLLYAAMLLPIYQNMEVQL

Nucleotide

Download Length: 1023 bp

                                >NTDB_id=888931 F6I35_RS01330 WP_171021869.1 230224..231246(+) (comYB) [Streptococcus anginosus strain UMB8616]

ATGCAGCAGGACATATCAATCTTGAGCAGGCAGAAGCGGAAAAAATTATCCACAGTTAGGCAGAAAAAGGTCGTAGAGTT

GCTGAATAATCTTTTTTCTAGTGGCTTTCATTTGGCAGAAATTATCGACTTTTTGAAGCGAAGTGCCTTGTTAGAAGAAG

TCTATGTGGACAGGATGAAAGAGGAGTTGTCAACAGGAAAGCCTTTTTCGGACATTATGGCAAGCTTAGGTTTTTCAGAT

AACGTGGTGACACAGCTTTCGCTGGCAGAATTACACGGAAATCTCTCACTCAGCCTGAGTAAGATTGAGGAATACTTGGA

AAATATCTCAAAAATTAAGAAGAAGTTGGTTGAAGTGGCGACTTATCCCTTTATTTTGTTTGTTTTTTTGATATTCATTA

TGCTGGGATTACGTAATTATTTACTCCCGCAACTCGATCGTCAAAATATAGCAACTCAGATTATCAGTAATTTGCCGCAA

CTTTTTCTGGGTTCATTAGGGGTAGTCTTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTCAAAAAAGCTCAAAAATAGC

AGTATTTCGTTTGTTAGCTCGCCTTCCTTTTTTGGGCGCTTTTATTCAAACCTATTTAACAGCTTATTATGCGAGAGAAT

GGGGGAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGACAACGCTCTGCTATGTTTCAA

GAAATTGGAAAAGATTTAGAAGTTGCGCTGCAAAATGGTCAGGAATTTTCGCAAAGAGTTAAAACATATCCATTTTTTAA

AAAGGAATTGGGCTTGATGATCGAATACGGTGAAGTAAAATCCAAATTGGGGTGTGAATTAGAAGTTTATGCCCAAAAAA

CATGGGAGACATTTTTTAAACGTGTTCATCAAGCGATGAATGTCATTCAACCACTAGTGTTTGTCTTTGTGGCTTTAATG

ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comYB	Streptococcus gordonii str. Challis substr. CH1	70.294	100	0.703
comGB/cglB	Streptococcus mitis SK321	68.657	98.529	0.676
comGB/cglB	Streptococcus mitis NCTC 12261	68.657	98.529	0.676
comGB/cglB	Streptococcus pneumoniae Rx1	67.761	98.529	0.668
comGB/cglB	Streptococcus pneumoniae D39	67.761	98.529	0.668
comGB/cglB	Streptococcus pneumoniae R6	67.761	98.529	0.668
comGB/cglB	Streptococcus pneumoniae TIGR4	67.761	98.529	0.668
comYB	Streptococcus mutans UA159	59.942	100	0.603
comYB	Streptococcus mutans UA140	59.649	100	0.6
comGB	Lactococcus lactis subsp. cremoris KW2	51.039	99.118	0.506

Detailed information NTG0888931