Detailed information NTG0885445

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: QN339_RS09350
• Genome accession: NZ_CP135104
• Coordinates: 1861148..1861900 (-)
• Length: 250 a.a.
• NCBI ID: WP_410534274.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain MA15
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1856148..1866900

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN339_RS09320 (QN339_09310)	-	1856205..1856696 (-)	492	WP_000632641.1	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	-
QN339_RS09325 (QN339_09315)	-	1856714..1857139 (-)	426	WP_000823117.1	PTS mannose transporter subunit IIA	-
QN339_RS09330 (QN339_09320)	-	1857386..1858420 (-)	1035	WP_000369175.1	acyltransferase family protein	-
QN339_RS09335 (QN339_09325)	-	1858649..1859803 (-)	1155	WP_000623425.1	ABC transporter permease subunit	-
QN339_RS09340 (QN339_09330)	-	1859809..1860657 (-)	849	WP_000926582.1	ABC transporter ATP-binding protein	-
QN339_RS09345 (QN339_09335)	-	1860780..1861079 (-)	300	WP_000002567.1	GHKL domain-containing protein	-
QN339_RS09350 (QN339_09340)	comE/blpR	1861148..1861900 (-)	753	WP_410534274.1	response regulator transcription factor	Regulator
QN339_RS09355 (QN339_09345)	-	1862175..1862990 (-)	816	WP_410534275.1	endonuclease/exonuclease/phosphatase family protein	-
QN339_RS09360 (QN339_09350)	-	1863044..1865227 (-)	2184	WP_000795065.1	PTS transporter subunit IIBC	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29719.29 Da
• Isoelectric Point: 7.8198

>NTDB_id=885445 QN339_RS09350 WP_410534274.1 1861148..1861900(-) (comE/blpR) [Streptococcus agalactiae strain MA15]
MNIFILEDDFVQQAHFEKIIKEIRVQYNLHFKTVETFAKPVQLLESIYEIGLHNLYFLDIEIKNDEQRGLEVAKQIRQID
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEAFSRRIEEVLLYVDGICNKPLVENSFYFKSRYSQVQLPFNDILY
IETSLRSHRVVLYTAKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRLVYFQNGTTCLVSRNKVRDIVSI
VDKYQKDRKR

Nucleotide

• Length: 753 bp

>NTDB_id=885445 QN339_RS09350 WP_410534274.1 1861148..1861900(-) (comE/blpR) [Streptococcus agalactiae strain MA15]
GTGAATATTTTTATACTTGAGGATGATTTTGTTCAACAAGCCCATTTTGAAAAAATCATTAAAGAGATTAGAGTACAGTA
CAATCTGCATTTCAAAACAGTAGAAACGTTTGCTAAACCAGTTCAATTATTGGAATCAATTTATGAAATAGGTTTACATA
ATTTATATTTCTTAGACATTGAAATAAAAAATGATGAGCAGAGGGGCTTAGAGGTCGCAAAACAAATTAGACAAATTGAT
CCTTATGCTCAGATTGTTTTTGTTACAACTCATTCGGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGCATTTAGCAGAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCA
ATAAGCCCTTAGTGGAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATATCCTTTAT
ATAGAAACGTCATTAAGGTCACATAGAGTTGTCCTTTATACTGCAAAAGACAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTGAATATTTTTAAAGTGGATA
GGATAGATAGATTAGTTTACTTCCAAAATGGAACGACTTGTCTGGTTTCACGCAATAAAGTGAGAGATATAGTATCTATA
GTGGATAAATATCAAAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	51.653	96.8	0.5
comE/comE1	Streptococcus equinus JB1	41.975	97.2	0.408
comE	Streptococcus infantis strain Atu-4	37.849	100	0.38
comE	Streptococcus mitis SK321	37.45	100	0.376
comE	Streptococcus mitis NCTC 12261	37.45	100	0.376
comE	Streptococcus pneumoniae D39	37.5	99.2	0.372
comE	Streptococcus pneumoniae Rx1	37.5	99.2	0.372
comE	Streptococcus pneumoniae R6	37.5	99.2	0.372
comE	Streptococcus pneumoniae TIGR4	37.5	99.2	0.372
comE/comE2	Streptococcus gordonii strain NCTC7865	37.449	97.2	0.364
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.449	97.2	0.364