Detailed information NTG0885268

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: QN325_RS03305
• Genome accession: NZ_CP135101
• Coordinates: 595932..596684 (+)
• Length: 250 a.a.
• NCBI ID: WP_410530758.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain HU13/21
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 590932..601684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN325_RS03295 (QN325_03285)	-	592603..594786 (+)	2184	WP_000795065.1	PTS transporter subunit IIBC	-
QN325_RS03300 (QN325_03290)	-	594840..595655 (+)	816	WP_001029865.1	endonuclease/exonuclease/phosphatase family protein	-
QN325_RS03305 (QN325_03295)	comE/blpR	595932..596684 (+)	753	WP_410530758.1	response regulator transcription factor	Regulator
QN325_RS03310 (QN325_03300)	-	596753..597051 (+)	299	Protein_577	GHKL domain-containing protein	-
QN325_RS03315 (QN325_03305)	-	597174..598022 (+)	849	WP_000926582.1	ABC transporter ATP-binding protein	-
QN325_RS03320 (QN325_03310)	-	598028..599182 (+)	1155	WP_000623425.1	ABC transporter permease subunit	-
QN325_RS03325 (QN325_03315)	-	599411..600445 (+)	1035	WP_000369175.1	acyltransferase family protein	-
QN325_RS03330 (QN325_03320)	-	600692..601117 (+)	426	WP_000823117.1	PTS mannose transporter subunit IIA	-
QN325_RS03335 (QN325_03325)	-	601135..601626 (+)	492	WP_000632641.1	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29732.35 Da
• Isoelectric Point: 8.2303

>NTDB_id=885268 QN325_RS03305 WP_410530758.1 595932..596684(+) (comE/blpR) [Streptococcus agalactiae strain HU13/21]
MNIFILEDDFVQQAHLEKIIKEIRVQYNLHFKTVETFAKPVQLLESIYEKGMHNLYFLDIEIKNDEQRGLEVAKQIRQID
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEAFSRRIEEVLLYVDGICNKPLVENSFYFKSRYSQVQLPFNDLLY
IETSLRSHRVVLYTAKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRLVYFQNGTTCLISRNKVRDIVSI
VDKYQKDRKR

Nucleotide

• Length: 753 bp

>NTDB_id=885268 QN325_RS03305 WP_410530758.1 595932..596684(+) (comE/blpR) [Streptococcus agalactiae strain HU13/21]
GTGAATATTTTTATACTTGAGGATGATTTTGTTCAACAAGCCCATTTGGAAAAAATCATTAAAGAGATTAGAGTACAGTA
CAATCTGCATTTCAAAACAGTAGAAACGTTTGCTAAACCAGTTCAATTATTGGAGTCAATTTATGAAAAAGGTATGCATA
ATTTATATTTCTTAGACATTGAAATAAAAAATGATGAGCAGAGGGGCTTAGAGGTCGCAAAACAAATTAGACAAATTGAT
CCTTATGCTCAGATTGTTTTTGTTACAACTCATTCGGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGCATTTAGCAGAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCA
ATAAGCCCTTAGTGGAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATCTCCTTTAT
ATAGAAACGTCATTAAGGTCACATAGAGTTGTCCTTTATACTGCAAAAGACAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTAAATATTTTTAAAGTGGATA
GGATAGATAGATTAGTTTACTTCCAAAATGGAACGACTTGTCTGATTTCACGCAATAAAGTGAGAGATATAGTATCTATA
GTGGATAAATATCAAAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-238)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.479	96.8	0.508
comE/comE1	Streptococcus equinus JB1	41.152	97.2	0.4
comE	Streptococcus pneumoniae D39	38.4	100	0.384
comE	Streptococcus pneumoniae R6	38.4	100	0.384
comE	Streptococcus pneumoniae Rx1	38.4	100	0.384
comE	Streptococcus pneumoniae TIGR4	38.4	100	0.384
comE	Streptococcus mitis SK321	38.4	100	0.384
comE	Streptococcus mitis NCTC 12261	38.4	100	0.384
comE	Streptococcus infantis strain Atu-4	38.247	100	0.384
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.449	97.2	0.364
comE/comE2	Streptococcus gordonii strain NCTC7865	37.449	97.2	0.364