Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   RMP67_RS03930 Genome accession   NZ_CP135087
Coordinates   777194..777856 (+) Length   220 a.a.
NCBI ID   WP_052502260.1    Uniprot ID   A0A116LCZ4
Organism   Streptococcus suis strain ID26102     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 772194..782856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP67_RS03910 (RMP67_03910) - 772910..773839 (-) 930 WP_024382739.1 ABC transporter substrate-binding protein -
  RMP67_RS03915 (RMP67_03915) - 773836..774636 (-) 801 WP_044668132.1 ABC transporter ATP-binding protein -
  RMP67_RS03920 (RMP67_03920) - 774788..776233 (-) 1446 WP_313921214.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  RMP67_RS03925 (RMP67_03925) - 776379..777125 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  RMP67_RS03930 (RMP67_03930) comEA/celA/cilE 777194..777856 (+) 663 WP_052502260.1 helix-hairpin-helix domain-containing protein Machinery gene
  RMP67_RS03935 (RMP67_03935) comEC/celB 777840..780077 (+) 2238 WP_313921215.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RMP67_RS03940 (RMP67_03940) holA 780173..781204 (+) 1032 WP_313921216.1 DNA polymerase III subunit delta -
  RMP67_RS03945 (RMP67_03945) sodA 781317..781922 (+) 606 WP_013730459.1 superoxide dismutase SodA -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23240.87 Da        Isoelectric Point: 4.0690

>NTDB_id=884873 RMP67_RS03930 WP_052502260.1 777194..777856(+) (comEA/celA/cilE) [Streptococcus suis strain ID26102]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEASEEPSQLVVDVK
GAVAKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVTSTATSSAMSSEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=884873 RMP67_RS03930 WP_052502260.1 777194..777856(+) (comEA/celA/cilE) [Streptococcus suis strain ID26102]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTTCCCGCAGTGGCTGGCTTGCT
AATGGCGACATTTTTAATCTTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGATTTTCCGCAGACCGCACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGCAAGTGAAGAGCCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCAGTAGCAAAGCCGGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAATATCTCGGTGGTGACCAGCACGGCTACCAGCTCTGCTATGTCCTCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAACACGGCGACTGAGGCGGACCTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAACGGCGGTTTCAAGTCGGTGGATGACCTCAACAATGTGTCGGGCATCGGCGACAAGACTATGGAAAGCATCC
GGCCTTATGTCACGGTTGACTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116LCZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae D39

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.541

99.091

0.491
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus mitis SK321

45.946

100

0.464
  comEA Streptococcus thermophilus LMD-9

59.494

71.818

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

38.938

100

0.4
  comEA Bacillus subtilis subsp. subtilis str. 168

38.571

95.455

0.368