Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   RMQ62_RS02400 Genome accession   NZ_CP135065
Coordinates   509086..509748 (-) Length   220 a.a.
NCBI ID   WP_313680742.1    Uniprot ID   -
Organism   Streptococcus suis strain ID24665     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 504086..514748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ62_RS02395 (RMQ62_02395) comEC/celB 506865..509102 (-) 2238 WP_313680744.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RMQ62_RS02400 (RMQ62_02400) comEA/celA/cilE 509086..509748 (-) 663 WP_313680742.1 helix-hairpin-helix domain-containing protein Machinery gene
  RMQ62_RS02405 (RMQ62_02405) - 509815..510561 (-) 747 WP_024407568.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  RMQ62_RS02410 (RMQ62_02410) - 510973..512418 (+) 1446 WP_313680740.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  RMQ62_RS02415 (RMQ62_02415) - 512570..513370 (+) 801 WP_313680739.1 ABC transporter ATP-binding protein -
  RMQ62_RS02420 (RMQ62_02420) - 513367..514296 (+) 930 WP_313680738.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23440.24 Da        Isoelectric Point: 4.1911

>NTDB_id=884710 RMQ62_RS02400 WP_313680742.1 509086..509748(-) (comEA/celA/cilE) [Streptococcus suis strain ID24665]
MDTIKTYIEMLKEYKWQIALPAVAGLLLTTFLIFSQPAKSDQTGLTDLPQTEQTSSSSELVEETSTEVSEEPSQLVVDVK
GAVAKPGLYTLKADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDEKISVVTSTTTSSAMSPEEKNTNLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=884710 RMQ62_RS02400 WP_313680742.1 509086..509748(-) (comEA/celA/cilE) [Streptococcus suis strain ID24665]
ATGGATACGATTAAAACTTATATTGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCAGCAGTTGCAGGTTTGCT
TCTGACAACATTCTTAATTTTCAGCCAACCAGCTAAGTCTGATCAGACAGGACTGACAGATTTACCACAGACCGAACAAA
CTTCTAGTAGCTCTGAGCTGGTCGAGGAAACCAGTACAGAAGTAAGTGAGGAGCCTAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTAGCAAAGCCAGGGCTCTACACTTTAAAAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGTGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAGGCGGTGGTCTATGTGGCTAGTAAAG
ATGAAAAAATCTCGGTGGTGACCAGCACGACTACCAGCTCTGCTATGTCCCCAGAAGAAAAAAACACTAATCTAGTCAAT
CTAAACACGGCGACCGAGGCTGACCTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGATATTATCGCCTATCG
TGAGGCAAACGGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTGTCGGGTATCGGCGACAAGACCATGGAAAGCATCC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(155-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae D39

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus mitis SK321

46.637

100

0.473
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

39.171

98.636

0.386
  comEA Bacillus subtilis subsp. subtilis str. 168

39.81

95.909

0.382