Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   RMQ62_RS02395 Genome accession   NZ_CP135065
Coordinates   506865..509102 (-) Length   745 a.a.
NCBI ID   WP_313680744.1    Uniprot ID   -
Organism   Streptococcus suis strain ID24665     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 501865..514102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ62_RS02395 (RMQ62_02395) comEC/celB 506865..509102 (-) 2238 WP_313680744.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RMQ62_RS02400 (RMQ62_02400) comEA/celA/cilE 509086..509748 (-) 663 WP_313680742.1 helix-hairpin-helix domain-containing protein Machinery gene
  RMQ62_RS02405 (RMQ62_02405) - 509815..510561 (-) 747 WP_024407568.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  RMQ62_RS02410 (RMQ62_02410) - 510973..512418 (+) 1446 WP_313680740.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  RMQ62_RS02415 (RMQ62_02415) - 512570..513370 (+) 801 WP_313680739.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83988.68 Da        Isoelectric Point: 6.5629

>NTDB_id=884709 RMQ62_RS02395 WP_313680744.1 506865..509102(-) (comEC/celB) [Streptococcus suis strain ID24665]
MSRLSKLPCQPIHLAILAVAAYFAVHSFSLLTMGLLSLLLVVFGFRQGKAVFLKTLPLLALCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQAYFQQLTDLVQLEVEAEVSLPAGQRNFNGFDYQDYL
KTQGIYRTVKLTAIKKIVPVQSWNIFDWLSSWRRQVLVYVKTNFPAPMSHYMTGLLFGDLDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETLDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLML
PRFLLTAGGVLTFTYAFLLTVFDFEDFGQVKKAVVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFIFDVLLLPGLSV
IFLLSPVVKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSGLVLLLLLVSLFMLYDFHRKKNWFLGLSLVLALLFFMTK
HPLENEVAVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFTAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLSHTDAD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPDLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=884709 RMQ62_RS02395 WP_313680744.1 506865..509102(-) (comEC/celB) [Streptococcus suis strain ID24665]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATTCACCTGGCAATCTTGGCGGTAGCGGCCTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGCTAAGTCTGTTACTAGTTGTCTTTGGGTTTCGGCAAGGCAAGGCAGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTGTGCGGTCTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGCCCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGACAGCCTGTCCTTTCGGGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGGCCTATTTTCAACAACTAACAGATCTAG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAACGGCTTTGACTATCAGGATTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACAGCGATTAAGAAGATTGTTCCTGTCCAGTCTTGGAACATTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAGGTCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTTTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTTTGGGCTTGACCAAGGAAAC
GTTGGATAAGTTGCAGATTCCCTTTTCTCTTGTCTACGCTGGTTTGACAGGCTTTTCGGTGTCAGTGGTGCGGTCCCTGG
TCCAGAAAATTCTGGGCAATATGGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTGTCTGTCTGCTGATGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGACTT
TGGGCAGGTCAAAAAGGCTGTGGTGGAAAGTCTCAGTATCTCGCTGGGGATTCTACCTGTGCTCATGACCTATTTCTATG
CCTTCCAGCCTCTGTCCATTCTCCTGACCTTTGCCTTTTCTTTTATCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATAACCTGGGTCAACGGATTTTTCGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGGGCTGGTTCTCTTGCTTTTGCTGGTCAGCCTCTTCA
TGCTTTACGATTTTCACAGGAAGAAAAACTGGTTCCTAGGACTAAGCCTGGTCCTCGCTCTGCTATTTTTCATGACCAAA
CACCCGCTGGAAAATGAGGTGGCGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGTCGGGTCGATTTTACGGCCAAGGAAGCTTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGAACCTTGATCCCTTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGAGCCATACCGACGCGGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTTCAGATTGGTCGGATTTACGTGTCGCCTGGAAGCCTGACGGTGCC
TGATTTTGTAGCGACCTTGAAAGAAATCAATGTCCCTGTTCATGTAGTGAAAGTAGGCGACCGTTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACGGGTGATGGTGGCAATAATGATTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACCAATTTCCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTAATAGAAACCTATCCTGACCTGCCTGTCGA
TGTCCTCAAAGCTGGTCACCATGGCTCCAAGGGCTCATCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCC
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGATAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAAGAGTGGAGGATTGAAACGGTGAGGGAGTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-460)

Domain of unknown function (DUF4131) (DUF4131)

(28-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.297

99.732

0.532
  comEC/celB Streptococcus mitis NCTC 12261

52.632

99.463

0.523
  comEC/celB Streptococcus pneumoniae TIGR4

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae Rx1

51.348

99.597

0.511
  comEC/celB Streptococcus pneumoniae D39

51.348

99.597

0.511
  comEC/celB Streptococcus pneumoniae R6

51.348

99.597

0.511
  comEC Lactococcus lactis subsp. cremoris KW2

48.069

100

0.485