Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   QN337_RS10055 Genome accession   NZ_CP134688
Coordinates   1982558..1983529 (+) Length   323 a.a.
NCBI ID   WP_047199570.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain MA07     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1977558..1988529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN337_RS10045 (QN337_10040) rpoC 1978256..1981906 (+) 3651 WP_000228729.1 DNA-directed RNA polymerase subunit beta' -
  QN337_RS10050 (QN337_10045) - 1982020..1982385 (+) 366 WP_000285373.1 DUF1033 family protein -
  QN337_RS10055 (QN337_10050) comYA 1982558..1983529 (+) 972 WP_047199570.1 competence type IV pilus ATPase ComGA Machinery gene
  QN337_RS10060 (QN337_10055) comYB 1983423..1984466 (+) 1044 WP_223295592.1 competence type IV pilus assembly protein ComGB Machinery gene
  QN337_RS10065 (QN337_10060) comYD 1984463..1984891 (+) 429 WP_000793381.1 competence type IV pilus minor pilin ComGD Machinery gene
  QN337_RS10070 (QN337_10065) comGE 1984863..1985162 (+) 300 WP_001867089.1 competence type IV pilus minor pilin ComGE -
  QN337_RS10075 (QN337_10070) comGF 1985116..1985577 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  QN337_RS10080 (QN337_10075) comGG 1985555..1985926 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  QN337_RS10085 (QN337_10080) comYH 1986041..1987015 (+) 975 WP_001008570.1 class I SAM-dependent methyltransferase Machinery gene
  QN337_RS10090 (QN337_10085) - 1987047..1988240 (+) 1194 WP_000047535.1 acetate kinase -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36809.25 Da        Isoelectric Point: 6.8469

>NTDB_id=882778 QN337_RS10055 WP_047199570.1 1982558..1983529(+) (comYA) [Streptococcus agalactiae strain MA07]
MVQSLAKQVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGTRGLYLFSSPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSISGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=882778 QN337_RS10055 WP_047199570.1 1982558..1983529(+) (comYA) [Streptococcus agalactiae strain MA07]
ATGGTTCAATCATTAGCAAAGCAAGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCGAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTACAAGAGGGC
TATATCTTTTTTCCAGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTTCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAACTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.167

96.285

0.656
  comYA Streptococcus mutans UA140

68.167

96.285

0.656
  comYA Streptococcus gordonii str. Challis substr. CH1

63.009

98.762

0.622
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.379

96.285

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.415

96.285

0.591
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.29

95.975

0.588
  comGA Lactococcus lactis subsp. cremoris KW2

50.311

99.69

0.502