Detailed information NTG0882779

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: QN337_RS10060
• Genome accession: NZ_CP134688
• Coordinates: 1983423..1984466 (+)
• Length: 347 a.a.
• NCBI ID: WP_223295592.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain MA07
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1978423..1989466

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN337_RS10050 (QN337_10045)	-	1982020..1982385 (+)	366	WP_000285373.1	DUF1033 family protein	-
QN337_RS10055 (QN337_10050)	comYA	1982558..1983529 (+)	972	WP_047199570.1	competence type IV pilus ATPase ComGA	Machinery gene
QN337_RS10060 (QN337_10055)	comYB	1983423..1984466 (+)	1044	WP_223295592.1	competence type IV pilus assembly protein ComGB	Machinery gene
QN337_RS10065 (QN337_10060)	comYD	1984463..1984891 (+)	429	WP_000793381.1	competence type IV pilus minor pilin ComGD	Machinery gene
QN337_RS10070 (QN337_10065)	comGE	1984863..1985162 (+)	300	WP_001867089.1	competence type IV pilus minor pilin ComGE	-
QN337_RS10075 (QN337_10070)	comGF	1985116..1985577 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	-
QN337_RS10080 (QN337_10075)	comGG	1985555..1985926 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	-
QN337_RS10085 (QN337_10080)	comYH	1986041..1987015 (+)	975	WP_001008570.1	class I SAM-dependent methyltransferase	Machinery gene
QN337_RS10090 (QN337_10085)	-	1987047..1988240 (+)	1194	WP_000047535.1	acetate kinase	-
QN337_RS10095 (QN337_10090)	-	1988391..1988597 (+)	207	WP_000798242.1	helix-turn-helix transcriptional regulator	-
QN337_RS10100 (QN337_10095)	-	1988656..1988799 (+)	144	WP_410534407.1	hypothetical protein	-
QN337_RS10105 (QN337_10100)	-	1988840..1989295 (+)	456	WP_000905674.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40005.70 Da
• Isoelectric Point: 9.9365

>NTDB_id=882779 QN337_RS10060 WP_223295592.1 1983423..1984466(+) (comYB) [Streptococcus agalactiae strain MA07]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDYYTDRMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLTFLVLIMIGLRHYLMPQLGENNFATS
LITNVPNIFLLLLAVVLIFSLIFYIVQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGVELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide

• Length: 1044 bp

>NTDB_id=882779 QN337_RS10060 WP_223295592.1 1983423..1984466(+) (comYB) [Streptococcus agalactiae strain MA07]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTATTATACAGATAGGATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGACTTTTCTGGTGCTAATTATGATTGGTCTTAGGCATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGC
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTGTTCA
AAAGCGATTGTCGCGTATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTGTTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCTGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

• Type II secretion system (T2SS), protein F (T2SSF) (33-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	61.877	98.271	0.608
comYB	Streptococcus mutans UA159	61.584	98.271	0.605
comYB	Streptococcus gordonii str. Challis substr. CH1	56.305	98.271	0.553
comGB/cglB	Streptococcus mitis NCTC 12261	54.925	96.542	0.53
comGB/cglB	Streptococcus mitis SK321	54.328	96.542	0.524
comGB/cglB	Streptococcus pneumoniae Rx1	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae D39	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae R6	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae TIGR4	53.433	96.542	0.516
comGB	Lactococcus lactis subsp. cremoris KW2	49.852	97.118	0.484