Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   RJW53_RS04640 Genome accession   NZ_CP134488
Coordinates   867200..867862 (+) Length   220 a.a.
NCBI ID   WP_023370712.1    Uniprot ID   A0AAP6A5A9
Organism   Streptococcus suis strain NLS50     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 862200..872862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS04620 (RJW53_04620) - 862918..863847 (-) 930 WP_023370720.1 ABC transporter substrate-binding protein -
  RJW53_RS04625 (RJW53_04625) - 863844..864644 (-) 801 WP_023370718.1 ABC transporter ATP-binding protein -
  RJW53_RS04630 (RJW53_04630) - 864796..866241 (-) 1446 WP_023370716.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  RJW53_RS04635 (RJW53_04635) - 866387..867133 (+) 747 WP_023370714.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  RJW53_RS04640 (RJW53_04640) comEA/celA/cilE 867200..867862 (+) 663 WP_023370712.1 helix-hairpin-helix domain-containing protein Machinery gene
  RJW53_RS04645 (RJW53_04645) comEC/celB 867846..870083 (+) 2238 WP_074389299.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RJW53_RS04650 (RJW53_04650) - 870100..870225 (+) 126 Protein_881 IS982 family transposase -
  RJW53_RS04655 (RJW53_04655) - 870408..871064 (+) 657 WP_011922763.1 CBS domain-containing protein -
  RJW53_RS04660 (RJW53_04660) - 871158..871985 (+) 828 WP_011922194.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23513.17 Da        Isoelectric Point: 4.0557

>NTDB_id=880317 RJW53_RS04640 WP_023370712.1 867200..867862(+) (comEA/celA/cilE) [Streptococcus suis strain NLS50]
MDTIKTYIEMLKEYKWQIALPTVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTSSSSDLVEETSTEVSEEPSQLVVDVK
GAVEKPGLYTLEVGSRVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTTSSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=880317 RJW53_RS04640 WP_023370712.1 867200..867862(+) (comEA/celA/cilE) [Streptococcus suis strain NLS50]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCAACAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATATTCAGCCAACCTGCTAAGTCTGACCAGACAGGACTGACAGACTTTCCACAGACCGAACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTGAGGAACCCAGCCAGCTGGTTGTTGATGTCAAA
GGAGCGGTGGAAAAACCAGGGCTTTACACTTTAGAAGTAGGTAGTCGTGTCAATGACGCAGTTGAGGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCAAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTGTCGGGCATCGGCGACAAGACTATGGAAAGCATCC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus pneumoniae D39

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus pneumoniae R6

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50.685

99.545

0.505
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.772

99.545

0.495
  comEA/celA/cilE Streptococcus mitis SK321

47.748

100

0.482
  comEA Streptococcus thermophilus LMD-9

59.494

71.818

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

38.71

98.636

0.382
  comEA Bacillus subtilis subsp. subtilis str. 168

37.915

95.909

0.364