Detailed information NTG0880318

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RJW53_RS04645
• Genome accession: NZ_CP134488
• Coordinates: 867846..870083 (+)
• Length: 745 a.a.
• NCBI ID: WP_074389299.1
• Uniprot ID: A0AAP6DW18
• Organism: Streptococcus suis strain NLS50
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 862846..875083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW53_RS04620 (RJW53_04620)	-	862918..863847 (-)	930	WP_023370720.1	ABC transporter substrate-binding protein	-
RJW53_RS04625 (RJW53_04625)	-	863844..864644 (-)	801	WP_023370718.1	ABC transporter ATP-binding protein	-
RJW53_RS04630 (RJW53_04630)	-	864796..866241 (-)	1446	WP_023370716.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
RJW53_RS04635 (RJW53_04635)	-	866387..867133 (+)	747	WP_023370714.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
RJW53_RS04640 (RJW53_04640)	comEA/celA/cilE	867200..867862 (+)	663	WP_023370712.1	helix-hairpin-helix domain-containing protein	Machinery gene
RJW53_RS04645 (RJW53_04645)	comEC/celB	867846..870083 (+)	2238	WP_074389299.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RJW53_RS04650 (RJW53_04650)	-	870100..870225 (+)	126	Protein_881	IS982 family transposase	-
RJW53_RS04655 (RJW53_04655)	-	870408..871064 (+)	657	WP_011922763.1	CBS domain-containing protein	-
RJW53_RS04660 (RJW53_04660)	-	871158..871985 (+)	828	WP_011922194.1	hypothetical protein	-
RJW53_RS04665 (RJW53_04665)	-	871991..873262 (+)	1272	WP_024405507.1	toxic anion resistance protein	-
RJW53_RS04670 (RJW53_04670)	-	873299..874165 (-)	867	WP_002935357.1	YitT family protein	-
RJW53_RS04675 (RJW53_04675)	tmk	874340..874978 (+)	639	WP_024379691.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84149.21 Da
• Isoelectric Point: 7.9211

>NTDB_id=880318 RJW53_RS04645 WP_074389299.1 867846..870083(+) (comEC/celB) [Streptococcus suis strain NLS50]
MSRLSKLPCQPIHLALLAVAAYFVVHSFSLLTMGLLSLLLLVFGFRQGKTVFIRTLPLIALCGLFFGYQKVQWERADQLA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYLTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPVPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=880318 RJW53_RS04645 WP_074389299.1 867846..870083(+) (comEC/celB) [Streptococcus suis strain NLS50]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATCCACTTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGACAAGGTAAGACAGTTTTCATCA
GAACGCTGCCGCTTATAGCCTTATGTGGTCTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGACAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGTCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTACCTG
AAAACACAGGGTATTTATCTGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGTTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCAGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGATGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.105	99.732	0.54
comEC/celB	Streptococcus mitis NCTC 12261	53.036	99.463	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.156	99.597	0.519
comEC/celB	Streptococcus pneumoniae Rx1	51.887	99.597	0.517
comEC/celB	Streptococcus pneumoniae D39	51.887	99.597	0.517
comEC/celB	Streptococcus pneumoniae R6	51.887	99.597	0.517
comEC	Lactococcus lactis subsp. cremoris KW2	49.13	100	0.493