Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   LTWDN19_RS09290 Genome accession   NZ_AP024685
Coordinates   1802430..1803305 (+) Length   291 a.a.
NCBI ID   WP_039099523.1    Uniprot ID   -
Organism   Latilactobacillus curvatus strain WDN19     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1797430..1808305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LTWDN19_RS09250 (LTWDN19_18460) - 1797535..1798362 (-) 828 WP_039099661.1 LysR family transcriptional regulator -
  LTWDN19_RS09255 (LTWDN19_18470) - 1798471..1799484 (+) 1014 WP_004265264.1 YeiH family protein -
  LTWDN19_RS09260 (LTWDN19_18480) - 1799575..1799814 (-) 240 WP_004270892.1 cytochrome b5 domain-containing protein -
  LTWDN19_RS09265 (LTWDN19_18490) - 1800009..1800344 (+) 336 WP_146954925.1 hypothetical protein -
  LTWDN19_RS09275 (LTWDN19_18500) - 1800525..1800902 (-) 378 WP_221276415.1 hypothetical protein -
  LTWDN19_RS09280 (LTWDN19_18510) - 1801005..1801505 (+) 501 WP_221276416.1 VanZ family protein -
  LTWDN19_RS09285 (LTWDN19_18520) - 1801595..1802326 (+) 732 WP_004270897.1 YebC/PmpR family DNA-binding transcriptional regulator -
  LTWDN19_RS09290 (LTWDN19_18530) comGA 1802430..1803305 (+) 876 WP_039099523.1 competence type IV pilus ATPase ComGA Machinery gene
  LTWDN19_RS09295 (LTWDN19_18540) comGB 1803295..1804296 (+) 1002 WP_146954924.1 type II secretion system F family protein Machinery gene
  LTWDN19_RS09300 (LTWDN19_18550) - 1804349..1805773 (-) 1425 WP_221276417.1 recombinase family protein -
  LTWDN19_RS10830 - 1805886..1806173 (-) 288 Protein_1796 Ltp family lipoprotein -
  LTWDN19_RS09310 (LTWDN19_18570) - 1806863..1807699 (-) 837 WP_221276418.1 hypothetical protein -
  LTWDN19_RS09315 (LTWDN19_18580) - 1807728..1808141 (-) 414 WP_146954920.1 ImmA/IrrE family metallo-endopeptidase -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 32042.84 Da        Isoelectric Point: 5.5654

>NTDB_id=87541 LTWDN19_RS09290 WP_039099523.1 1802430..1803305(+) (comGA) [Latilactobacillus curvatus strain WDN19]
MTEVLTTLLQKCATEKAQDLYFRPLSTGWAIIERLATGLKPLQKVTLSEGNQWLNQMKYQAGMDISETRRPQTGRSAIEV
AGELIYLRLATVGDFLNRESLVVRFIYPIGQTYHCDDSQILSRLMQLIQQPGLLLFAGPTGSGKTTSLYYLAEQVMQDKM
VVAIEDPIEIQQPAFLQLQVNEAAGLTYAALLKISLRLRPDTLIIGEIRDLQTAQHAVSAALSGHLVLSTIHARSTTGVM
DRLLDLGISHSQLTACLAGVAYQSLVVDGHNVAAHYELATAQQLEEAVHED

Nucleotide


Download         Length: 876 bp        

>NTDB_id=87541 LTWDN19_RS09290 WP_039099523.1 1802430..1803305(+) (comGA) [Latilactobacillus curvatus strain WDN19]
ATGACCGAAGTATTAACAACCCTTTTGCAAAAGTGCGCAACGGAAAAAGCGCAGGATCTTTATTTTCGACCACTATCGAC
GGGTTGGGCAATTATTGAACGCTTAGCGACAGGACTAAAGCCGTTACAAAAAGTTACTCTGTCAGAAGGCAATCAATGGC
TCAATCAAATGAAGTATCAAGCGGGGATGGATATCAGTGAAACTCGGCGTCCACAGACCGGCCGTTCAGCGATCGAGGTG
GCAGGCGAATTGATTTATTTACGGTTGGCAACCGTGGGGGATTTTTTGAATCGGGAAAGTTTAGTTGTTCGTTTCATTTA
TCCCATTGGGCAGACTTATCATTGCGACGACTCGCAGATTTTAAGTCGTTTAATGCAGTTAATTCAGCAACCAGGATTAT
TGCTATTTGCCGGTCCAACTGGTTCAGGGAAGACAACAAGTTTGTACTATCTTGCGGAACAAGTCATGCAAGATAAGATG
GTGGTTGCGATTGAAGATCCGATAGAGATTCAACAGCCAGCGTTCTTACAGTTACAAGTGAATGAAGCCGCAGGGTTAAC
CTATGCAGCATTGTTGAAAATCAGTTTGCGATTACGGCCTGATACCTTAATTATTGGTGAGATTCGCGACTTACAGACGG
CCCAACACGCGGTTTCTGCGGCGTTGAGCGGTCACTTGGTACTAAGTACGATTCACGCGCGAAGTACAACGGGGGTGATG
GACCGTCTATTAGATCTTGGAATTAGCCACTCACAATTAACCGCTTGTTTAGCGGGTGTTGCCTATCAATCACTAGTGGT
CGACGGCCACAATGTAGCGGCCCACTATGAGTTAGCAACTGCACAACAATTGGAGGAGGCTGTTCATGAAGACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Latilactobacillus sakei subsp. sakei 23K

69.892

95.876

0.67
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

43.015

93.471

0.402
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

42.593

92.784

0.395
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae R6

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae D39

41.573

91.753

0.381
  comGA Lactococcus lactis subsp. cremoris KW2

41.603

90.034

0.375
  comYA Streptococcus mutans UA140

37.113

100

0.371
  comYA Streptococcus mutans UA159

37.113

100

0.371
  comYA Streptococcus gordonii str. Challis substr. CH1

39.194

93.814

0.368

Multiple sequence alignment