Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   LACPH_RS04250 Genome accession   NZ_CP132482
Coordinates   875531..876772 (+) Length   413 a.a.
NCBI ID   WP_274784593.1    Uniprot ID   -
Organism   Lacticaseibacillus parahuelsenbergensis strain NCIMB 15471     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 852699..886339 875531..876772 within 0


Gene organization within MGE regions


Location: 852699..886339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LACPH_RS04130 (LACPH_000826) - 852896..853531 (-) 636 WP_274784578.1 DsbA family protein -
  LACPH_RS04135 (LACPH_000827) - 853601..854194 (-) 594 WP_274784579.1 CYTH domain-containing protein -
  LACPH_RS04140 (LACPH_000828) - 854361..855038 (+) 678 WP_010489529.1 GTP pyrophosphokinase family protein -
  LACPH_RS04145 (LACPH_000829) - 855040..855837 (+) 798 WP_010489527.1 NAD kinase -
  LACPH_RS04150 (LACPH_000830) - 855837..856739 (+) 903 WP_274784580.1 RluA family pseudouridine synthase -
  LACPH_RS04155 (LACPH_000831) - 856844..857902 (-) 1059 WP_274784588.1 FAD:protein FMN transferase -
  LACPH_RS04160 (LACPH_000832) - 858120..858755 (-) 636 WP_274784581.1 copper homeostasis protein CutC -
  LACPH_RS04165 (LACPH_000833) - 858776..859594 (-) 819 WP_025012504.1 undecaprenyl-diphosphate phosphatase -
  LACPH_RS04170 (LACPH_000834) - 859652..859786 (+) 135 WP_306387267.1 hypothetical protein -
  LACPH_RS04175 (LACPH_000835) - 859815..860855 (-) 1041 WP_306387268.1 lactonase family protein -
  LACPH_RS04180 (LACPH_000836) - 861123..861497 (+) 375 WP_274784583.1 PTS glucitol/sorbitol transporter subunit IIA -
  LACPH_RS04185 (LACPH_000837) rpsN 861593..861862 (-) 270 WP_003564153.1 30S ribosomal protein S14 -
  LACPH_RS04190 (LACPH_000838) - 861979..862956 (-) 978 WP_032958395.1 GMP reductase -
  LACPH_RS04195 (LACPH_000839) - 863151..864098 (-) 948 WP_010489474.1 magnesium transporter CorA family protein -
  LACPH_RS04200 (LACPH_000840) - 864165..865007 (+) 843 WP_274784584.1 methyltransferase domain-containing protein -
  LACPH_RS04205 (LACPH_000841) - 865088..866545 (-) 1458 WP_306387269.1 ISNCY family transposase -
  LACPH_RS04210 (LACPH_000842) trmL 867000..867509 (+) 510 WP_049169083.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
  LACPH_RS04215 (LACPH_000843) - 867532..867939 (+) 408 WP_087911825.1 DUF1149 family protein -
  LACPH_RS04220 (LACPH_000844) - 868044..870356 (+) 2313 WP_274784589.1 DNA translocase FtsK -
  LACPH_RS04225 (LACPH_000845) yfmF 870365..871627 (+) 1263 WP_306387270.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  LACPH_RS04230 (LACPH_000846) yfmH 871624..872919 (+) 1296 WP_274784591.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  LACPH_RS04235 (LACPH_000847) ymfI 872916..873644 (+) 729 WP_274784592.1 elongation factor P 5-aminopentanone reductase -
  LACPH_RS04240 (LACPH_000848) - 873731..874669 (+) 939 WP_049169078.1 helix-turn-helix domain-containing protein -
  LACPH_RS04245 (LACPH_000849) pgsA 874666..875259 (+) 594 WP_025012513.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LACPH_RS04250 (LACPH_000850) cinA 875531..876772 (+) 1242 WP_274784593.1 competence/damage-inducible protein A Machinery gene
  LACPH_RS04255 (LACPH_000851) recA 876827..877870 (+) 1044 WP_087911832.1 recombinase RecA Machinery gene
  LACPH_RS04260 (LACPH_000852) rny 878471..880042 (+) 1572 WP_010489446.1 ribonuclease Y -
  LACPH_RS04265 (LACPH_000853) - 880188..880841 (-) 654 WP_274784594.1 YigZ family protein -
  LACPH_RS04270 (LACPH_000854) - 880869..882131 (+) 1263 WP_274784595.1 DEAD/DEAH box helicase -
  LACPH_RS04275 (LACPH_000855) - 882289..882807 (+) 519 WP_274784596.1 ComF family protein -
  LACPH_RS04280 (LACPH_000856) hpf 882932..883489 (+) 558 WP_010489439.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LACPH_RS04285 (LACPH_000857) secA 883758..886121 (+) 2364 WP_039638826.1 preprotein translocase subunit SecA -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44150.50 Da        Isoelectric Point: 6.3712

>NTDB_id=869185 LACPH_RS04250 WP_274784593.1 875531..876772(+) (cinA) [Lacticaseibacillus parahuelsenbergensis strain NCIMB 15471]
MQAEIIAVGTEILMGQITNTNGAYMAKQLAALGIASYHQQVVGDNAQRLADAISLAEKRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNKLQAMYPQGADTLVNRVGLAVGAWVEQHQHAYVLLPGPPKEFIPMV
DHELLPHLAKYSGHHEAFVSRVMRFFGVGESQLVTDLGDLIAKQTNPTLATYIKDHEVTIRVTASGETQADAEAKLEPVI
GAIMDREGRYFYGYGDDNSLAKELVKALAATDKQITAAESLTAGAFQAALGDVPGVSDYFKGGFVTYALATKAAFLNIDA
RELAAHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDTLEGQPAGTVWIGLARMGQAPVAQIYHFPGGRNDVRKRAV
MTGMMIALKSLRD

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=869185 LACPH_RS04250 WP_274784593.1 875531..876772(+) (cinA) [Lacticaseibacillus parahuelsenbergensis strain NCIMB 15471]
ATGCAAGCAGAAATTATTGCTGTCGGAACTGAAATTCTGATGGGACAGATTACTAATACTAATGGCGCCTATATGGCTAA
ACAGTTGGCCGCTTTAGGCATTGCCAGCTATCATCAACAGGTTGTCGGTGACAATGCGCAACGCCTGGCTGATGCGATCA
GCTTAGCCGAAAAACGCAGTGACATTGTGATTTTGATCGGTGGTTTAGGACCCACACCAGATGACCTGACGAAACAAACG
TTGGCGGCTCATCTGAATTTGCCATTGGTTGAAGATGCGGACGCCATGGCAAAACTGGCGGCGCGGGTTAAACAACAGCA
GCGGCCGATGACGCCAAATAATAAGTTACAGGCGATGTATCCGCAAGGTGCTGATACATTGGTTAATCGCGTCGGGCTGG
CAGTCGGTGCCTGGGTCGAACAACACCAACATGCCTATGTACTACTGCCTGGGCCGCCTAAGGAATTTATCCCAATGGTT
GATCATGAGCTATTGCCTCATTTGGCCAAGTATAGCGGCCATCATGAAGCTTTTGTCAGCCGCGTCATGCGCTTCTTTGG
TGTTGGTGAATCACAATTGGTGACGGATTTGGGTGATTTAATTGCCAAGCAGACGAATCCGACACTGGCAACGTATATCA
AGGATCATGAAGTGACCATTCGGGTGACGGCTAGCGGTGAGACCCAAGCAGATGCTGAAGCCAAACTGGAACCGGTGATC
GGTGCCATTATGGATCGTGAGGGACGTTACTTTTATGGTTATGGTGATGATAATAGCCTCGCTAAAGAGTTGGTCAAGGC
ATTAGCGGCGACCGATAAGCAAATAACAGCAGCGGAGAGTTTGACGGCCGGTGCGTTCCAGGCGGCTTTGGGGGATGTTC
CCGGCGTTTCGGATTATTTCAAAGGCGGTTTTGTGACGTACGCCTTAGCCACTAAAGCAGCATTTTTGAATATTGATGCG
CGTGAGTTAGCGGCTCATGGGGTAGTGAGTGAATTTACTGCCAAAGCAATGGCCGAGCACGCCCGTCAGCGGGCTGCGGC
CGATATTGCAGTCAGTTTTACCGGCGTGGCCGGGCCCGACACACTGGAAGGGCAGCCAGCCGGGACAGTTTGGATCGGCT
TGGCGCGGATGGGCCAAGCGCCGGTTGCACAGATTTATCATTTTCCCGGTGGCCGCAATGATGTTCGCAAACGCGCGGTT
ATGACCGGCATGATGATCGCATTGAAGAGCTTGCGGGATTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

50.594

100

0.516
  cinA Streptococcus mitis NCTC 12261

50.594

100

0.516
  cinA Streptococcus mutans UA159

50.725

100

0.508
  cinA Streptococcus pneumoniae TIGR4

49.881

100

0.508
  cinA Streptococcus pneumoniae Rx1

49.406

100

0.504
  cinA Streptococcus pneumoniae R6

49.406

100

0.504
  cinA Streptococcus pneumoniae D39

49.169

100

0.501
  cinA Bacillus subtilis subsp. subtilis str. 168

44.878

99.274

0.446
  cinA Streptococcus suis isolate S10

42.147

92.494

0.39