Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   STYK_RS01065 Genome accession   NZ_AP024523
Coordinates   212013..212315 (+) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 207013..217315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS01035 (STYK_01830) - 207770..208828 (+) 1059 WP_261805079.1 zinc-dependent alcohol dehydrogenase family protein -
  STYK_RS01040 (STYK_01840) - 208978..209343 (+) 366 WP_000286405.1 DUF1033 family protein -
  STYK_RS01045 (STYK_01850) comGA/cglA/cilD 209420..210361 (+) 942 WP_261805080.1 competence type IV pilus ATPase ComGA Machinery gene
  STYK_RS01050 (STYK_01860) comGB/cglB 210309..211325 (+) 1017 WP_261805081.1 competence type IV pilus assembly protein ComGB Machinery gene
  STYK_RS01055 (STYK_01870) comGC/cglC 211327..211653 (+) 327 WP_004257466.1 competence type IV pilus major pilin ComGC Machinery gene
  STYK_RS01060 (STYK_01880) comGD/cglD 211646..212050 (+) 405 WP_261081317.1 competence type IV pilus minor pilin ComGD Machinery gene
  STYK_RS01065 (STYK_01890) comGE/cglE 212013..212315 (+) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  STYK_RS01070 (STYK_01900) comGF/cglF 212278..212739 (+) 462 WP_261805082.1 competence type IV pilus minor pilin ComGF Machinery gene
  STYK_RS01075 (STYK_01910) comGG/cglG 212717..213130 (+) 414 WP_261805083.1 competence type IV pilus minor pilin ComGG Machinery gene
  STYK_RS01080 (STYK_01920) - 213163..213750 (+) 588 WP_261805084.1 class I SAM-dependent methyltransferase -
  STYK_RS01085 (STYK_01930) comYH 213811..214764 (+) 954 WP_049515760.1 class I SAM-dependent methyltransferase Machinery gene
  STYK_RS01090 (STYK_01940) - 214815..216005 (+) 1191 WP_033684718.1 acetate kinase -
  STYK_RS01095 (STYK_01950) rnpA 216155..216526 (+) 372 WP_033679593.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=85713 STYK_RS01065 WP_000413380.1 212013..212315(+) (comGE/cglE) [Streptococcus toyakuensis strain TP1632]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=85713 STYK_RS01065 WP_000413380.1 212013..212315(+) (comGE/cglE) [Streptococcus toyakuensis strain TP1632]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTTGCTCTAGCTATCTT
TGCTAGCATTGCGACCCTTCTTTTGGGACAAATTCAGAAAAATAGACAAGAAGAAGCAAAAATTTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATCAACGGAGTTGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTTTATCATGGCTCAGAACAGTTGTTGGCTATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment