Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   V6U68_RS09420 Genome accession   NZ_CP145866
Coordinates   2016671..2017612 (-) Length   313 a.a.
NCBI ID   WP_201041167.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2011671..2022612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS09380 (V6U68_09360) - 2011746..2012939 (-) 1194 WP_003095894.1 acetate kinase -
  V6U68_RS09385 (V6U68_09365) comGH 2012996..2013952 (-) 957 WP_037601477.1 class I SAM-dependent methyltransferase Machinery gene
  V6U68_RS09390 (V6U68_09370) comGG 2013997..2014314 (-) 318 WP_041817287.1 competence type IV pilus minor pilin ComGG Machinery gene
  V6U68_RS09395 (V6U68_09375) comGF 2014292..2014729 (-) 438 WP_080611747.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U68_RS09400 (V6U68_09380) comGE 2014716..2015006 (-) 291 WP_195435963.1 competence type IV pilus minor pilin ComGE Machinery gene
  V6U68_RS09405 (V6U68_09385) comGD 2014978..2015406 (-) 429 WP_267472584.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U68_RS09410 (V6U68_09390) comGC 2015366..2015692 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U68_RS09415 (V6U68_09395) comGB 2015689..2016789 (-) 1101 WP_410531677.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U68_RS09420 (V6U68_09400) comGA 2016671..2017612 (-) 942 WP_201041167.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U68_RS09425 (V6U68_09405) - 2017692..2018054 (-) 363 WP_073949471.1 DUF1033 family protein -
  V6U68_RS09430 (V6U68_09410) - 2018266..2019515 (+) 1250 Protein_1801 ISL3 family transposase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35270.27 Da        Isoelectric Point: 5.4492

>NTDB_id=853901 V6U68_RS09420 WP_201041167.1 2016671..2017612(-) (comGA) [Streptococcus salivarius strain KSS9]
MVTEFAKEMIKNADSCGAQDIYVIPRQDTYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=853901 V6U68_RS09420 WP_201041167.1 2016671..2017612(-) (comGA) [Streptococcus salivarius strain KSS9]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATACTTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACTGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCTGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGTCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus mutans UA159

65.176

100

0.652
  comGA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comGA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361