Detailed information NTG0851756

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V6S38_RS06230
• Genome accession: NZ_CP145662
• Coordinates: 1249927..1252776 (+)
• Length: 949 a.a.
• NCBI ID: WP_273658943.1
• Uniprot ID: -
• Organism: Escherichia coli strain S1-INA-02-B
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1244927..1257776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6S38_RS06190 (V6S38_06190)	-	1245488..1246521 (-)	1034	Protein_1193	IS5 family transposase	-
V6S38_RS06195 (V6S38_06195)	-	1246555..1247301 (-)	747	Protein_1194	DUF4158 domain-containing protein	-
V6S38_RS06200 (V6S38_06200)	-	1247299..1247613 (+)	315	Protein_1195	helix-turn-helix domain-containing protein	-
V6S38_RS06205 (V6S38_06205)	-	1247708..1247785 (+)	78	Protein_1196	3'-5' exonuclease	-
V6S38_RS06210 (V6S38_06210)	-	1247991..1248626 (-)	636	Protein_1197	IS1 family transposase	-
V6S38_RS06215 (V6S38_06215)	-	1248701..1248802 (-)	102	Protein_1198	IS1 family transposase	-
V6S38_RS06220 (V6S38_06220)	-	1248936..1249217 (+)	282	WP_000643630.1	helix-turn-helix domain-containing protein	-
V6S38_RS06225 (V6S38_06225)	hsp20	1249252..1249821 (+)	570	WP_000350436.1	small heat shock protein sHSP20	-
V6S38_RS06230 (V6S38_06230)	clpC	1249927..1252776 (+)	2850	WP_273658943.1	heat shock survival AAA family ATPase ClpK	Regulator
V6S38_RS06235 (V6S38_06235)	-	1252776..1252988 (+)	213	WP_000896642.1	hypothetical protein	-
V6S38_RS06240 (V6S38_06240)	-	1253012..1254157 (+)	1146	WP_004118192.1	hypothetical protein	-
V6S38_RS06245 (V6S38_06245)	trx-GI	1254147..1254587 (+)	441	WP_000786815.1	heat resistance system thioredoxin Trx-GI	-
V6S38_RS06250 (V6S38_06250)	kefB-GI	1254591..1256300 (+)	1710	WP_033554001.1	heat resistance system K+/H+ antiporter KefB-GI	-
V6S38_RS06255 (V6S38_06255)	psiE-GI	1256303..1256800 (+)	498	WP_000837725.1	heat resistance protein PsiE-GI	-
V6S38_RS06260 (V6S38_06260)	-	1256778..1257248 (+)	471	Protein_1207	M48 family metalloprotease	-
V6S38_RS06265 (V6S38_06265)	-	1257303..1257616 (-)	314	Protein_1208	Tn3 family transposase	-

Sequence

Protein

• Length: 949 a.a.
• Molecular weight: 104591.28 Da
• Isoelectric Point: 5.5794

>NTDB_id=851756 V6S38_RS06230 WP_273658943.1 1249927..1252776(+) (clpC) [Escherichia coli strain S1-INA-02-B]
MARKQCQVCGQPATVRVEANLNGRNSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGEDATPVAA
DTDDVVDASFGEPATAGSGAPRRRGSGLVSRISEQSEALLQEAAKHAAEFGRSEVDTEHLLLALADSDVVKTILGQFKIK
VDDLKRQIESEARRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMARDGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQSELILFIDEVHTIVGAGQGGGEGGLD
VANVFKPMMARGELNLIGATTLNEYQKYIEKDAALERRFQPVTVPEPTVAQTIMILRGLRDTFEAHHKVSISEDAIIAAA
ELSDRYITARFLPDKAIDLLDQAAARVKLSATARPVAVQELESELHQLRREQDYVAARKQYDQAAELGKRIEAKEAELKK
LVEDWERERASGSAEVKAEHVAQVVSRLTGIPVNELTVEEREKLLHLEQRLHERLVGQDEAVRAVADAVRLSRAGLREGS
KPVATFLFLGPTGVGKTELAKALAESIYGDEHALLRIDMSEYGERHTVARLVGAPPGYVGYDEGGQLTEKVRRKPYSVLL
LDEIEKAHPDVYNILLQVFDDGRLTDGKGRVVNFTNTIIIATSNLGSDIIQRRLKAREAAGEEYEKTKAEVMDVLRGHFR
PEFLNRIDEIIVFHALGKEEIRHIVGLQLDRVARSAASQDVTLTFDQTLIDHFAEEGYKPEFGARELKRLIRSELETALA
REMLGGGIGKGDHASARWDDKAERVVFERKEPPQTPAEPEQPDVAKATETPHGDAGKDSSKKKSASDAS

Nucleotide

• Length: 2850 bp

>NTDB_id=851756 V6S38_RS06230 WP_273658943.1 1249927..1252776(+) (clpC) [Escherichia coli strain S1-INA-02-B]
ATGGCCAGAAAACAATGCCAGGTCTGCGGCCAACCCGCCACCGTGCGGGTGGAAGCCAATCTCAACGGTCGTAACAGCAC
CATGCTGTTGTGCGACGACCATTACCGGCAATTAGTGCGCCAGCAAAAGCGCACCGTTTCGCCGCTGGAAGCCTTGTTCG
GCTCGCGCAGCGGCCTGTTCGAGGACTTCCTTGGCAGTGACTTCTTCCGCATCGGCGAAGACGCGACGCCAGTTGCCGCC
GATACCGATGACGTGGTCGATGCCTCGTTTGGCGAGCCCGCCACCGCAGGTTCGGGTGCGCCGCGCCGTCGCGGCAGTGG
GTTGGTCAGCCGCATCAGCGAACAGTCGGAAGCCTTGCTGCAGGAGGCCGCCAAACACGCTGCCGAATTTGGCCGCTCCG
AGGTGGATACCGAACATCTGCTGCTGGCGCTGGCCGACAGCGACGTGGTCAAGACCATCCTGGGTCAGTTCAAGATCAAG
GTCGATGACCTCAAGCGGCAGATCGAGTCTGAGGCCAGGCGCGGGGACAAGCCCTTCGAGGGCGAGATCGGCGTGTCGCC
GCGCGTGAAGGATGCGCTCAGCCGCGCCTTCGTGGCCTCCAATGAACTCGGCCATTCTTATGTCGGTCCAGAGCATTTCC
TGATCGGTCTGGCCGAGGAAGGCGAAGGGCTGGCCGCCAACCTGCTGCGCCGCTACGGCCTGACGCCGCAGGCGCTGCGC
CAACAGGTCAGCAAGGTGGTCGGCAAGGGCGCCGAGGATGGCCGCGCTGAGACGCCGACCAACACGCCAGAACTCGACAA
GTACTCGCGCGACCTGACCAAGATGGCGCGCGACGGCAAGCTCGACCCGGTGATCGGCCGCGCGCAGGAGATCGAAACCA
CCATCGAGGTGCTGGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCGGGTGTGGGCAAGACCGCCATCGTC
GAAGGGCTGGCGCAGCGCATGGTGGCGGGTGAAGTGCCCGAGACCTTGCGCGACAAGCGCCTGGTGGAACTCAACATCAA
CGCCATGGTGGCCGGCGCCAAATATCGCGGCGAGTTCGAGGAGCGCGTGCAGAAGGTGCTGAAGGAGGTGACCGAGCACC
AGAGCGAGCTGATTTTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGTGGCGAAGGCGGGCTGGAC
GTGGCCAACGTGTTCAAACCGATGATGGCGCGCGGTGAACTCAACCTGATCGGCGCCACGACGCTGAACGAGTACCAGAA
ATACATCGAGAAGGATGCCGCACTGGAGCGGCGCTTCCAGCCGGTGACGGTGCCCGAGCCGACGGTGGCCCAGACCATCA
TGATTCTGCGCGGCCTGCGCGACACCTTCGAGGCGCACCACAAGGTCAGCATCTCCGAGGACGCGATCATCGCGGCGGCC
GAGTTGTCCGACCGCTACATCACGGCGCGCTTCCTGCCGGACAAGGCGATCGACCTGCTCGACCAGGCGGCCGCGCGCGT
GAAGCTGTCGGCCACGGCCCGGCCGGTGGCCGTGCAGGAGCTGGAGTCCGAACTGCACCAGCTACGGCGTGAACAGGATT
ACGTGGCCGCGCGCAAGCAGTACGACCAGGCCGCCGAGCTCGGCAAGCGCATCGAAGCCAAGGAGGCCGAGCTCAAGAAG
CTCGTCGAGGACTGGGAGCGGGAGCGGGCCTCCGGCAGTGCCGAGGTCAAGGCGGAACACGTGGCGCAGGTTGTCTCGCG
CCTGACCGGCATCCCGGTCAACGAGTTGACGGTGGAAGAGCGCGAAAAGCTGCTGCACTTGGAACAACGGCTGCACGAGC
GCCTGGTGGGACAAGACGAGGCGGTCCGTGCCGTGGCCGATGCCGTGCGGCTATCCCGCGCCGGCCTGCGCGAAGGCAGT
AAACCGGTGGCTACCTTCCTGTTTCTGGGCCCGACCGGGGTGGGCAAGACCGAGCTCGCCAAGGCATTGGCCGAATCGAT
CTACGGCGATGAGCACGCCCTGTTGCGCATCGACATGTCGGAATATGGCGAACGCCATACCGTGGCGCGGCTGGTGGGCG
CGCCTCCGGGCTATGTCGGTTACGACGAAGGCGGTCAGCTCACCGAGAAGGTGCGGCGCAAGCCCTACAGCGTGCTGCTG
CTCGACGAGATCGAGAAGGCACACCCTGACGTCTACAACATCCTGCTGCAAGTGTTTGACGACGGTCGCCTCACCGACGG
CAAGGGCCGGGTGGTGAATTTCACCAACACCATCATCATCGCCACGTCCAACCTGGGTTCGGACATCATCCAGCGACGGC
TGAAGGCGCGTGAGGCGGCTGGCGAGGAGTACGAAAAGACCAAGGCCGAGGTCATGGACGTGCTGCGCGGCCACTTCCGG
CCCGAGTTCCTCAACCGCATCGACGAGATCATCGTCTTCCATGCGCTGGGCAAGGAGGAGATCCGCCACATCGTCGGCCT
GCAGCTCGATCGCGTGGCGCGCAGCGCCGCCAGCCAGGACGTGACGCTCACTTTCGATCAGACGCTGATCGACCATTTCG
CGGAAGAAGGCTACAAGCCCGAGTTCGGTGCGCGTGAACTCAAGCGCCTGATCCGCAGCGAGCTGGAAACTGCGCTGGCG
CGCGAGATGCTCGGTGGCGGCATCGGCAAGGGCGATCACGCCAGCGCACGCTGGGACGACAAGGCCGAACGCGTGGTGTT
CGAACGCAAAGAGCCACCGCAGACCCCGGCCGAGCCGGAGCAGCCGGATGTCGCGAAGGCGACCGAGACGCCGCACGGCG
ACGCTGGCAAAGACTCGAGCAAGAAGAAGTCGGCGAGCGACGCATCTTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (307-428)

• AAA lid domain (AAA_lid_9) (449-547)

• AAA domain (Cdc48 subfamily) (AAA_2) (641-810)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (816-894)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (123-171)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (199-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.627	84.089	0.426
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.494	85.037	0.37
clpC	Streptococcus thermophilus LMD-9	41.787	87.25	0.365
clpC	Streptococcus thermophilus LMG 18311	41.697	86.934	0.362