Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   QU606_RS12065 Genome accession   NZ_CP128996
Coordinates   2648841..2650049 (+) Length   402 a.a.
NCBI ID   WP_193690171.1    Uniprot ID   A0A7M2JAD5
Organism   Pseudomonas sp. OVF7     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2643841..2655049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QU606_RS12040 (QU606_12040) nadC 2645244..2646092 (+) 849 WP_024073388.1 carboxylating nicotinate-nucleotide diphosphorylase -
  QU606_RS12045 (QU606_12045) - 2646214..2646519 (-) 306 WP_024073387.1 DUF6388 family protein -
  QU606_RS12055 (QU606_12055) - 2646782..2648191 (-) 1410 WP_304998420.1 O-antigen ligase -
  QU606_RS12060 (QU606_12060) - 2648226..2648639 (-) 414 WP_024073385.1 pilin -
  QU606_RS12065 (QU606_12065) pilC 2648841..2650049 (+) 1209 WP_193690171.1 type II secretion system F family protein Machinery gene
  QU606_RS12070 (QU606_12070) pilD 2650046..2650912 (+) 867 WP_069075202.1 A24 family peptidase Machinery gene
  QU606_RS12075 (QU606_12075) coaE 2650909..2651532 (+) 624 WP_024073382.1 dephospho-CoA kinase -
  QU606_RS12080 (QU606_12080) yacG 2651529..2651729 (+) 201 WP_017845472.1 DNA gyrase inhibitor YacG -
  QU606_RS12085 (QU606_12085) - 2651726..2651941 (-) 216 WP_003171680.1 hypothetical protein -
  QU606_RS12090 (QU606_12090) - 2652018..2652707 (-) 690 WP_024073381.1 energy-coupling factor ABC transporter permease -
  QU606_RS12095 (QU606_12095) - 2652704..2653171 (-) 468 WP_069075203.1 FAD/FMN-containing dehydrogenase -
  QU606_RS12100 (QU606_12100) - 2653272..2653901 (+) 630 WP_017845475.1 DUF1780 domain-containing protein -
  QU606_RS12105 (QU606_12105) - 2653991..2654164 (+) 174 WP_024073379.1 DUF3094 family protein -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 43305.57 Da        Isoelectric Point: 9.9822

>NTDB_id=850367 QU606_RS12065 WP_193690171.1 2648841..2650049(+) (pilC) [Pseudomonas sp. OVF7]
MDNASRTYAWEGTNRQGHRVSGHTTGHNLALIKAKLRQQGIRPSSVRRQFPGLACLAAPIKPTDIALLTRQLATLLKAGI
PLLQAFDIISDGFESRPMQELLKGLTQDIAAGTALATALRKQPRYFDDLYCNLIAAGEQAGALETLLERVATHLEKSEQL
KARIKKAMTYPIAVLVVASLVSSILLIHVVPQFQNLFAGVDRQLPGFTLHVIGLSTFMQQAWWALALGLGAGFFALRHAY
RVAPGFRQGLDTGLLKAPLAGTLLKKSAVARYARTLSTTFAAGVPLVQALDSVAGAVGNGPYKQAIKHMRHEVSTGMQLN
QSMAASGLFPGMAIQMTAIGEESGTLERMLEKVANHYESEVDNLVDNLTSLMEPLIMVVLGGIVGALVIAMYLPVFQLGT
AF

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=850367 QU606_RS12065 WP_193690171.1 2648841..2650049(+) (pilC) [Pseudomonas sp. OVF7]
ATGGACAACGCTTCAAGGACCTACGCGTGGGAAGGCACCAACCGCCAGGGGCACAGGGTGTCCGGGCACACCACGGGCCA
CAACCTCGCCCTGATCAAGGCAAAGCTGCGCCAGCAAGGGATCCGCCCCAGCAGCGTGCGCAGGCAATTCCCCGGCCTGG
CCTGCCTCGCCGCGCCGATCAAACCCACTGACATCGCCCTGCTCACCCGCCAGTTGGCGACCTTGCTGAAAGCCGGCATT
CCTCTGCTGCAAGCCTTCGACATCATCAGCGACGGCTTCGAGAGCCGGCCGATGCAGGAACTGCTCAAGGGGTTGACGCA
GGACATCGCCGCCGGCACCGCACTGGCGACCGCGCTGCGCAAACAGCCACGCTATTTCGATGACCTGTACTGCAACCTGA
TTGCCGCCGGCGAACAGGCCGGGGCATTGGAAACGCTGTTGGAGCGCGTTGCCACTCACCTGGAAAAGAGTGAGCAGCTA
AAGGCGCGAATCAAGAAAGCCATGACCTACCCGATCGCCGTCCTGGTGGTGGCGAGCCTGGTCAGCAGCATCCTGCTGAT
CCACGTAGTGCCGCAATTTCAGAACCTGTTCGCCGGAGTCGACCGACAGTTGCCCGGTTTTACCCTGCACGTCATCGGCC
TGTCCACGTTCATGCAGCAAGCCTGGTGGGCTCTGGCGCTTGGCCTCGGGGCCGGTTTTTTCGCGCTGCGCCACGCCTAT
CGCGTAGCCCCTGGCTTTCGTCAGGGGCTGGATACGGGTTTGTTGAAAGCCCCCTTGGCAGGCACACTGCTGAAGAAATC
GGCCGTGGCACGCTATGCCCGCACGCTTTCCACCACGTTCGCGGCTGGGGTGCCGCTGGTACAGGCATTGGATTCAGTGG
CAGGTGCCGTCGGCAACGGGCCGTACAAGCAGGCGATCAAACATATGCGTCATGAGGTATCCACAGGCATGCAGTTGAAC
CAATCCATGGCCGCCAGCGGTCTCTTTCCAGGCATGGCAATTCAGATGACGGCCATCGGCGAGGAGTCGGGCACACTCGA
GCGCATGCTGGAAAAAGTCGCGAACCACTATGAATCGGAAGTCGACAACCTGGTCGACAACCTCACCAGCCTGATGGAGC
CGCTGATAATGGTGGTGCTGGGGGGCATTGTCGGGGCGCTGGTAATTGCGATGTACCTGCCGGTCTTCCAACTCGGTACA
GCGTTTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(69-191)

Type II secretion system (T2SS), protein F (T2SSF)

(273-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7M2JAD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.071

98.507

0.562
  pilC Acinetobacter baylyi ADP1

51.759

99.005

0.512
  pilC Acinetobacter baumannii D1279779

49.747

98.507

0.49
  pilC Legionella pneumophila strain ERS1305867

48.99

98.507

0.483
  pilC Vibrio cholerae strain A1552

40.351

99.254

0.4
  pilG Neisseria gonorrhoeae MS11

38.539

98.756

0.381
  pilC Vibrio campbellii strain DS40M4

38.442

99.005

0.381
  pilC Thermus thermophilus HB27

37.656

99.751

0.376
  pilG Neisseria meningitidis 44/76-A

38.035

98.756

0.376