Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   QWH96_RS00665 Genome accession   NZ_CP128987
Coordinates   110946..111887 (+) Length   313 a.a.
NCBI ID   WP_338433685.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NS3396     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 105946..116887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWH96_RS00655 (QWH96_00655) rpoC 106658..110299 (+) 3642 WP_049519674.1 DNA-directed RNA polymerase subunit beta' -
  QWH96_RS00660 (QWH96_00660) - 110500..110865 (+) 366 WP_003055257.1 DUF1033 family protein -
  QWH96_RS00665 (QWH96_00665) comGA/cglA 110946..111887 (+) 942 WP_338433685.1 competence type IV pilus ATPase ComGA Machinery gene
  QWH96_RS00670 (QWH96_00670) comYB 111823..112854 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  QWH96_RS00675 (QWH96_00675) comYC 112856..113182 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  QWH96_RS00680 (QWH96_00680) comGD 113157..113585 (+) 429 WP_049519672.1 competence type IV pilus minor pilin ComGD -
  QWH96_RS00685 (QWH96_00685) comGE 113593..113838 (+) 246 WP_049519695.1 competence type IV pilus minor pilin ComGE -
  QWH96_RS00690 (QWH96_00690) comGF 113819..114259 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  QWH96_RS00695 (QWH96_00695) comGG 114282..114611 (+) 330 WP_338433753.1 competence type IV pilus minor pilin ComGG -
  QWH96_RS00700 (QWH96_00700) comYH 114674..115627 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  QWH96_RS00705 (QWH96_00705) - 115686..116882 (+) 1197 WP_003058485.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35106.24 Da        Isoelectric Point: 7.2704

>NTDB_id=850156 QWH96_RS00665 WP_338433685.1 110946..111887(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MVQALARSILKEAEQIQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGGDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLCLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARFEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=850156 QWH96_RS00665 WP_338433685.1 110946..111887(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGGAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTGTCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAAGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

99.042

0.61
  comYA Streptococcus mutans UA159

61.093

99.361

0.607
  comYA Streptococcus mutans UA140

61.093

99.361

0.607
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.908

93.61

0.364