Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   L6410_RS00455 Genome accession   NZ_AP024276
Coordinates   81392..82573 (+) Length   393 a.a.
NCBI ID   WP_237395575.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SUT-286     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 76392..87573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6410_RS00440 (SUT286_00710) mutL 77707..79644 (+) 1938 WP_237396594.1 DNA mismatch repair endonuclease MutL -
  L6410_RS00445 (SUT286_00720) ruvA 79683..80273 (+) 591 WP_237395572.1 Holliday junction branch migration protein RuvA -
  L6410_RS00450 (SUT286_00730) - 80787..81356 (+) 570 WP_237395574.1 DNA-3-methyladenine glycosylase I -
  L6410_RS00455 (SUT286_00740) cinA 81392..82573 (+) 1182 WP_237395575.1 competence/damage-inducible protein A Machinery gene
  L6410_RS00460 (SUT286_00750) recA 82625..83779 (+) 1155 WP_024392836.1 recombinase RecA Machinery gene
  L6410_RS00465 (SUT286_00760) spx 83994..84392 (+) 399 WP_024392835.1 transcriptional regulator Spx -
  L6410_RS00470 (SUT286_00770) - 84502..84768 (+) 267 WP_024392834.1 IreB family regulatory phosphoprotein -
  L6410_RS00475 (SUT286_00780) ruvX 84768..85187 (+) 420 WP_079269042.1 Holliday junction resolvase RuvX -
  L6410_RS00480 (SUT286_00790) - 85199..85519 (+) 321 WP_024392832.1 DUF1292 domain-containing protein -
  L6410_RS00485 (SUT286_00800) - 85844..86392 (+) 549 WP_237395576.1 nucleotidyltransferase family protein -
  L6410_RS00490 (SUT286_00810) comX/sigX 86575..87045 (+) 471 WP_024392830.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42827.64 Da        Isoelectric Point: 4.3355

>NTDB_id=84455 L6410_RS00455 WP_237395575.1 81392..82573(+) (cinA) [Streptococcus parasuis strain SUT-286]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDMVILCGGLGPTEDDLTKQT
LATFLQKELVVDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMLEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRDFFYAYGDDNSLVKTVATLLEEEKQSLGILEHGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVEPESTIDNVLARVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=84455 L6410_RS00455 WP_237395575.1 81392..82573(+) (cinA) [Streptococcus parasuis strain SUT-286]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATTGATGTATACTTCCACACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTACTTG
AAATTGCAAGTAAACGGAGTGATATGGTCATTTTATGTGGTGGTTTAGGTCCAACTGAAGACGACTTGACTAAGCAAACT
TTAGCAACATTTTTGCAAAAGGAGTTGGTTGTTGACGAACTAGCGATGGCAAAATTAGACCGTTTCTTTGCCAGTCGACC
AGGTCGAGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTTGGTGGTATGCTTGAGCAAGATGGTGTGACCTATATTGTTTTGCCCGGACCACCAAGTGAACTCAAGGCTATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAGCAACTTTACTCGCGTGTCCTACGCTTTTTTGGCATTGG
CGAAAGCCAGTTGGTAACTGTTTTGGCTGACTTGATTGACAAGCAGACAGACCCGACTCTTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTATCTACGAAGGCAGATAGTCAGGAAGAAGCGAACGTGCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGATTTTTTCTATGCATATGGGGATGATAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAGAGAAACAATCTTTGGGCATCCTAGAGCATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGCGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGTTATCAGAAGAAGCA
AGTCGTATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTAGTGTCGGTGGCAGTCGAGCCAGAATCAACAATAGACAA
CGTACTTGCTAGAGTATATCTAGCCTTGGCCAGTACCTCGGGGATTTCCAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGACAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-252)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

86.768

100

0.868
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae TIGR4

55.288

100

0.585
  cinA Streptococcus pneumoniae Rx1

55.288

100

0.585
  cinA Streptococcus pneumoniae R6

55.288

100

0.585
  cinA Streptococcus pneumoniae D39

55.048

100

0.583
  cinA Streptococcus mutans UA159

55.231

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

46.906

78.117

0.366

Multiple sequence alignment