Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   VF946_RS05675 Genome accession   NZ_CP141824
Coordinates   1077676..1078338 (-) Length   220 a.a.
NCBI ID   WP_024405509.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1072676..1083338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS05650 - 1073142..1073591 (+) 450 WP_242952495.1 hypothetical protein -
  VF946_RS05655 - 1073642..1073893 (-) 252 WP_002294510.1 hypothetical protein -
  VF946_RS05660 - 1074017..1075171 (-) 1155 WP_105140797.1 helix-turn-helix domain-containing protein -
  VF946_RS05665 - 1075253..1075888 (-) 636 WP_105140796.1 CpXC domain-containing protein -
  VF946_RS05670 comEC/celB 1076013..1077692 (-) 1680 WP_395424540.1 ComEC/Rec2 family competence protein Machinery gene
  VF946_RS05675 comEA/celA/cilE 1077676..1078338 (-) 663 WP_024405509.1 helix-hairpin-helix domain-containing protein Machinery gene
  VF946_RS05680 - 1078405..1079151 (-) 747 WP_014735985.1 lysophospholipid acyltransferase family protein -
  VF946_RS05685 - 1079297..1080742 (+) 1446 WP_024405510.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  VF946_RS05690 - 1080894..1081679 (+) 786 WP_011922762.1 ABC transporter ATP-binding protein -
  VF946_RS05695 - 1081692..1082621 (+) 930 WP_238716824.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23233.97 Da        Isoelectric Point: 4.1447

>NTDB_id=838183 VF946_RS05675 WP_024405509.1 1077676..1078338(-) (comEA/celA/cilE) [Streptococcus suis strain HB18]
MDTIKTYIEMLKEYKWQIALPTVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEASEEPSQLVVDVK
GAVVKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVNDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=838183 VF946_RS05675 WP_024405509.1 1077676..1078338(-) (comEA/celA/cilE) [Streptococcus suis strain HB18]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCACAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGATTTTCCGCAGACCGCACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGCAAGTGAGGAACCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGGCTCTACACTTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTAGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCTCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCAAACGGTGGCTTCAAGTCGGTGAACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(157-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae D39

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae R6

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.624

99.091

0.482
  comEA/celA/cilE Streptococcus mitis SK321

45.946

100

0.464
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

36.283

100

0.373
  comEA Bacillus subtilis subsp. subtilis str. 168

37.915

95.909

0.364