Detailed information NTG0838051

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: LL303_RS12285
• Genome accession: NZ_CP126467
• Coordinates: 2385387..2386460 (-)
• Length: 357 a.a.
• NCBI ID: WP_095348492.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain 303
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2380387..2391460

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL303_RS12240 (LL303_12210)	-	2380526..2381335 (-)	810	WP_010906310.1	metal ABC transporter permease	-
LL303_RS12245 (LL303_12215)	-	2381328..2382065 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
LL303_RS12250 (LL303_12220)	-	2382242..2383084 (-)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
LL303_RS12255 (LL303_12225)	-	2383081..2383518 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
LL303_RS12260 (LL303_12230)	comGG	2383599..2383883 (-)	285	WP_010906314.1	competence type IV pilus minor pilin ComGG	Machinery gene
LL303_RS12265 (LL303_12235)	comGF	2383922..2384368 (-)	447	WP_031558968.1	competence type IV pilus minor pilin ComGF	Machinery gene
LL303_RS12270 (LL303_12240)	comGE	2384331..2384627 (-)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
LL303_RS12275 (LL303_12245)	comGD	2384599..2384997 (-)	399	WP_023164614.1	competence type IV pilus minor pilin ComGD	Machinery gene
LL303_RS12280 (LL303_12250)	comGC	2384990..2385373 (-)	384	WP_010906318.1	competence type IV pilus major pilin ComGC	Machinery gene
LL303_RS12285 (LL303_12255)	comGB	2385387..2386460 (-)	1074	WP_095348492.1	competence type IV pilus assembly protein ComGB	Machinery gene
LL303_RS12290 (LL303_12260)	comGA	2386354..2387292 (-)	939	WP_031561106.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 40356.59 Da
• Isoelectric Point: 10.3000

>NTDB_id=838051 LL303_RS12285 WP_095348492.1 2385387..2386460(-) (comGB) [Lactococcus lactis subsp. lactis strain 303]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQALSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFLEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide

• Length: 1074 bp

>NTDB_id=838051 LL303_RS12285 WP_095348492.1 2385387..2386460(-) (comGB) [Lactococcus lactis subsp. lactis strain 303]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTTAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCGGGAATATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (227-348)

• Type II secretion system (T2SS), protein F (T2SSF) (41-159)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	83.578	95.518	0.798
comYB	Streptococcus gordonii str. Challis substr. CH1	53.959	95.518	0.515
comYB	Streptococcus mutans UA140	53.372	95.518	0.51
comYB	Streptococcus mutans UA159	53.079	95.518	0.507
comGB/cglB	Streptococcus mitis SK321	51.343	93.838	0.482
comGB/cglB	Streptococcus pneumoniae TIGR4	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae Rx1	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae D39	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae R6	51.045	93.838	0.479
comGB/cglB	Streptococcus mitis NCTC 12261	50.448	93.838	0.473