Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   U2S93_RS26590 Genome accession   NZ_CP140431
Coordinates   5597448..5598665 (+) Length   405 a.a.
NCBI ID   WP_010792214.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain 2023CK-01249     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5592448..5603665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2S93_RS26570 (U2S93_26570) nadC 5594039..5594887 (+) 849 WP_022579594.1 carboxylating nicotinate-nucleotide diphosphorylase -
  U2S93_RS26580 (U2S93_26580) pilE 5595040..5595513 (-) 474 WP_015503553.1 pilin Machinery gene
  U2S93_RS26585 (U2S93_26585) pilB 5595744..5597444 (+) 1701 WP_015503554.1 type IV-A pilus assembly ATPase PilB Machinery gene
  U2S93_RS26590 (U2S93_26590) pilC 5597448..5598665 (+) 1218 WP_010792214.1 type II secretion system F family protein Machinery gene
  U2S93_RS26595 (U2S93_26595) pilD 5598668..5599540 (+) 873 WP_015503555.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  U2S93_RS26600 (U2S93_26600) coaE 5599537..5600148 (+) 612 WP_003094654.1 dephospho-CoA kinase -
  U2S93_RS26605 (U2S93_26605) yacG 5600145..5600345 (+) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  U2S93_RS26610 (U2S93_26610) - 5600382..5600591 (-) 210 WP_003094660.1 hypothetical protein -
  U2S93_RS26615 (U2S93_26615) - 5600697..5601386 (-) 690 WP_003094662.1 energy-coupling factor ABC transporter permease -
  U2S93_RS26620 (U2S93_26620) - 5601383..5601853 (-) 471 WP_003094664.1 hypothetical protein -
  U2S93_RS26625 (U2S93_26625) - 5601850..5602275 (-) 426 WP_003103865.1 GNAT family N-acetyltransferase -
  U2S93_RS26630 (U2S93_26630) - 5602408..5603037 (+) 630 WP_003094668.1 DUF1780 domain-containing protein -
  U2S93_RS26635 (U2S93_26635) - 5603034..5603483 (+) 450 WP_003094670.1 MOSC domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44242.19 Da        Isoelectric Point: 9.8988

>NTDB_id=834772 U2S93_RS26590 WP_010792214.1 5597448..5598665(+) (pilC) [Pseudomonas aeruginosa strain 2023CK-01249]
MADKALKTCVFVWEGTDKKGAKVKGELAGQNTMLVKAQLRKQGINPLKVRKKGITLLGKGKRVKPMDIALFTRQMATMMG
AGVPLLQSFDIISEGFDNPNMRKLVDEIKQEVSAGNSLANSLRKKPLYFDDLYCNLVDAGEQSGALETLLDRVATYKEKT
ESLKAKIKKAMTYPIAVVLVAIIVSAILLIKVVPQFQSVFSSFGAELPAFTMMVINLSNLLQEWWLVVLIGLFSASFAIK
ESHKRSVNFRNTVDRYMLKIPIIGGILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRNAVSKIKQDVSTGM
QLNFSMRTTNVFPNMAIQMTAIGEESGSLDDMLGKVAAFYEEEVDNAVDNLTTLMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGSVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=834772 U2S93_RS26590 WP_010792214.1 5597448..5598665(+) (pilC) [Pseudomonas aeruginosa strain 2023CK-01249]
ATGGCGGATAAAGCGTTAAAAACCTGTGTTTTCGTCTGGGAAGGCACGGACAAGAAAGGGGCAAAGGTCAAGGGGGAGTT
GGCTGGCCAGAACACTATGCTGGTGAAGGCGCAACTGCGCAAACAGGGCATAAATCCGCTCAAGGTCAGAAAAAAGGGCA
TTACCCTTCTCGGCAAGGGAAAGCGCGTAAAGCCGATGGACATCGCACTATTTACTCGTCAGATGGCAACCATGATGGGT
GCTGGGGTTCCTCTCTTGCAATCGTTCGACATAATCTCCGAAGGTTTCGACAATCCCAACATGCGTAAGCTGGTCGACGA
GATCAAACAAGAGGTCTCGGCGGGTAACAGCCTGGCAAACTCCTTGCGAAAGAAACCTCTTTATTTTGACGATCTCTATT
GCAACCTGGTGGATGCAGGTGAACAATCTGGCGCCTTGGAGACTTTGCTTGACCGTGTTGCCACCTATAAGGAAAAAACC
GAATCGCTAAAAGCCAAGATAAAAAAGGCTATGACATACCCCATTGCCGTCGTCTTGGTCGCGATCATTGTTTCAGCCAT
TCTCCTGATCAAGGTCGTCCCTCAGTTCCAATCCGTTTTCTCCAGTTTCGGAGCGGAACTACCAGCCTTTACAATGATGG
TGATAAACCTGTCAAATCTTTTACAGGAATGGTGGCTAGTCGTCCTCATCGGATTATTCAGCGCCAGCTTCGCCATCAAG
GAATCGCATAAGCGTTCAGTAAATTTCCGTAACACGGTAGACCGCTATATGTTGAAAATACCGATAATCGGAGGAATACT
TTACAAATCAGCCGTGGCACGTTACGCCCGTACACTTTCAACAACTTTCGCCGCAGGTGTTCCATTGGTGGAGGCACTAG
ACTCTGTCTCTGGAGCGACAGGAAACGTGGTATTCCGCAACGCGGTAAGCAAGATCAAACAGGATGTATCCACAGGTATG
CAATTGAACTTCTCCATGAGAACGACCAATGTATTCCCCAACATGGCAATCCAGATGACAGCCATCGGTGAGGAATCCGG
TTCTCTGGACGACATGTTGGGCAAGGTGGCTGCGTTCTATGAGGAGGAAGTAGACAATGCCGTCGACAATCTGACAACTC
TCATGGAACCTATGATCATGGCCGTTCTCGGCGTACTGGTCGGCGGCCTGATCATCGCTATGTATCTACCGATCTTCCAA
CTGGGTTCCGTTGTGTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

78.765

100

0.788
  pilC Acinetobacter baumannii D1279779

58.911

99.753

0.588
  pilC Acinetobacter baylyi ADP1

59.045

98.272

0.58
  pilC Legionella pneumophila strain ERS1305867

54.293

97.778

0.531
  pilG Neisseria meningitidis 44/76-A

44.03

99.259

0.437
  pilG Neisseria gonorrhoeae MS11

43.781

99.259

0.435
  pilC Vibrio cholerae strain A1552

43.21

100

0.432
  pilC Vibrio campbellii strain DS40M4

43.182

97.778

0.422
  pilC Thermus thermophilus HB27

37.406

99.012

0.37