Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QL280_RS08850 Genome accession   NZ_CP125291
Coordinates   1731668..1732924 (-) Length   418 a.a.
NCBI ID   WP_000642708.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 105_Kz     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1726668..1737924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL280_RS08825 (QL280_08825) - 1726725..1726931 (-) 207 WP_000366093.1 hypothetical protein -
  QL280_RS08830 (QL280_08830) - 1726918..1727079 (-) 162 WP_000289348.1 helix-turn-helix transcriptional regulator -
  QL280_RS08835 (QL280_08835) lytA 1727438..1728394 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  QL280_RS08840 (QL280_08840) - 1728770..1730140 (-) 1371 WP_001036292.1 MATE family efflux transporter -
  QL280_RS08845 (QL280_08845) recA 1730447..1731613 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  QL280_RS08850 (QL280_08850) cinA 1731668..1732924 (-) 1257 WP_000642708.1 competence/damage-inducible protein A Machinery gene
  QL280_RS08855 (QL280_08855) - 1733009..1734025 (-) 1017 WP_000239282.1 LCP family protein -
  QL280_RS08860 (QL280_08860) - 1734033..1734551 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  QL280_RS08865 (QL280_08865) tsaE 1734541..1734984 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  QL280_RS08870 (QL280_08870) comM 1735070..1735690 (-) 621 WP_000839908.1 hypothetical protein Regulator
  QL280_RS08875 (QL280_08875) - 1736073..1736936 (-) 864 WP_001093618.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45091.48 Da        Isoelectric Point: 4.6027

>NTDB_id=830843 QL280_RS08850 WP_000642708.1 1731668..1732924(-) (cinA) [Streptococcus pneumoniae strain 105_Kz]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKTLLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=830843 QL280_RS08850 WP_000642708.1 1731668..1732924(-) (cinA) [Streptococcus pneumoniae strain 105_Kz]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGACTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae Rx1

99.282

100

0.993
  cinA Streptococcus pneumoniae R6

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.043

100

0.99
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

71.292

100

0.713
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455