Detailed information
Bioinformatically predicted
Overview
| Name | comYA | Type | Machinery gene |
| Locus tag | H7676_RS00650 | Genome accession | NZ_AP023390 |
| Coordinates | 101667..102620 (+) | Length | 317 a.a. |
| NCBI ID | WP_184492312.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain KUN-0014944 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 96667..107620
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7676_RS00640 (KUN4944_00780) | rpoC | 97416..101057 (+) | 3642 | WP_031488660.1 | DNA-directed RNA polymerase subunit beta' | - |
| H7676_RS00645 (KUN4944_00790) | - | 101209..101574 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| H7676_RS00650 (KUN4944_00800) | comYA | 101667..102620 (+) | 954 | WP_184492312.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| H7676_RS00655 (KUN4944_00810) | comYB | 102556..103590 (+) | 1035 | WP_226316548.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| H7676_RS00660 (KUN4944_00820) | comYC | 103592..103918 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| H7676_RS00665 (KUN4944_00830) | comGD | 103893..104321 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| H7676_RS00670 (KUN4944_00840) | comGE | 104278..104562 (+) | 285 | WP_011284422.1 | competence type IV pilus minor pilin ComGE | - |
| H7676_RS00675 (KUN4944_00850) | comYF | 104555..104989 (+) | 435 | WP_020904833.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| H7676_RS00680 (KUN4944_00860) | comGG | 104973..105299 (+) | 327 | WP_002986539.1 | competence type IV pilus minor pilin ComGG | - |
| H7676_RS00685 (KUN4944_00870) | comYH | 105397..106350 (+) | 954 | WP_010921802.1 | class I SAM-dependent methyltransferase | Machinery gene |
| H7676_RS00690 (KUN4944_00880) | - | 106409..107605 (+) | 1197 | WP_020904834.1 | acetate kinase | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35537.93 Da Isoelectric Point: 8.8671
>NTDB_id=82818 H7676_RS00650 WP_184492312.1 101667..102620(+) (comYA) [Streptococcus pyogenes strain KUN-0014944]
MVQALAKAILAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVG
SCDYKLSKDKQLSLRLSSVGDYRGHESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISS
YHQEAQVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAK
SISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII
MVQALAKAILAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVG
SCDYKLSKDKQLSLRLSSVGDYRGHESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISS
YHQEAQVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAK
SISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII
Nucleotide
Download Length: 954 bp
>NTDB_id=82818 H7676_RS00650 WP_184492312.1 101667..102620(+) (comYA) [Streptococcus pyogenes strain KUN-0014944]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTA
TATTTTGCCAAGAGCAGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCG
ATCGGATGGCTCCTCTTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGT
TCATGTGATTATAAGCTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCATGAAAG
CTTAGTGATTCGTCTGCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAG
TTGGCGGTAGAGGGTTGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGT
TATCATCAAGAAGCACAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAA
TGATGATATTGGTATGACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGA
TTCGAGATAGTCAAACAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAA
AGTATCTCGGGTGTTTATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGC
TTACCAAAGGTTACTTAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGA
ATCAACAAATTGATCAGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTA
TATTTTGCCAAGAGCAGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCG
ATCGGATGGCTCCTCTTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGT
TCATGTGATTATAAGCTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCATGAAAG
CTTAGTGATTCGTCTGCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAG
TTGGCGGTAGAGGGTTGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGT
TATCATCAAGAAGCACAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAA
TGATGATATTGGTATGACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGA
TTCGAGATAGTCAAACAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAA
AGTATCTCGGGTGTTTATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGC
TTACCAAAGGTTACTTAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGA
ATCAACAAATTGATCAGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYA | Streptococcus mutans UA140 |
60.759 |
99.685 |
0.606 |
| comYA | Streptococcus mutans UA159 |
60.759 |
99.685 |
0.606 |
| comGA/cglA | Streptococcus sobrinus strain NIDR 6715-7 |
60.586 |
96.845 |
0.587 |
| comYA | Streptococcus gordonii str. Challis substr. CH1 |
60.586 |
96.845 |
0.587 |
| comGA/cglA/cilD | Streptococcus mitis NCTC 12261 |
59.935 |
96.845 |
0.58 |
| comGA/cglA/cilD | Streptococcus pneumoniae Rx1 |
59.283 |
96.845 |
0.574 |
| comGA/cglA/cilD | Streptococcus pneumoniae D39 |
59.283 |
96.845 |
0.574 |
| comGA/cglA/cilD | Streptococcus pneumoniae R6 |
59.283 |
96.845 |
0.574 |
| comGA/cglA/cilD | Streptococcus pneumoniae TIGR4 |
59.283 |
96.845 |
0.574 |
| comGA | Lactococcus lactis subsp. cremoris KW2 |
50 |
99.685 |
0.498 |
| comGA | Latilactobacillus sakei subsp. sakei 23K |
39.655 |
91.483 |
0.363 |