Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QBE57_RS08435 Genome accession   NZ_CP121670
Coordinates   1716851..1718032 (-) Length   393 a.a.
NCBI ID   WP_012774894.1    Uniprot ID   -
Organism   Streptococcus suis strain HBXY-SL     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1711851..1723032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBE57_RS08395 rpsJ 1712140..1712448 (-) 309 WP_011922546.1 30S ribosomal protein S10 -
  QBE57_RS08400 comX/sigX 1712772..1713038 (-) 267 WP_014635810.1 hypothetical protein Regulator
  QBE57_RS08405 - 1713111..1713689 (-) 579 WP_012774895.1 nucleotidyltransferase family protein -
  QBE57_RS08410 - 1713897..1714217 (-) 321 WP_002939343.1 DUF1292 domain-containing protein -
  QBE57_RS08415 ruvX 1714229..1714648 (-) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  QBE57_RS08420 - 1714648..1714914 (-) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  QBE57_RS08425 spx 1715014..1715412 (-) 399 WP_002939362.1 transcriptional regulator Spx -
  QBE57_RS08430 recA 1715648..1716799 (-) 1152 WP_011922545.1 recombinase RecA Machinery gene
  QBE57_RS08435 cinA 1716851..1718032 (-) 1182 WP_012774894.1 competence/damage-inducible protein A Machinery gene
  QBE57_RS08440 - 1718069..1718638 (-) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  QBE57_RS08445 ruvA 1719363..1719953 (-) 591 WP_011921679.1 Holliday junction branch migration protein RuvA -
  QBE57_RS08450 mutL 1719992..1721929 (-) 1938 WP_012774891.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42862.76 Da        Isoelectric Point: 4.3975

>NTDB_id=813802 QBE57_RS08435 WP_012774894.1 1716851..1718032(-) (cinA) [Streptococcus suis strain HBXY-SL]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADVIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=813802 QBE57_RS08435 WP_012774894.1 1716851..1718032(-) (cinA) [Streptococcus suis strain HBXY-SL]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTTCATACGGCAGTTGGTGACAATGAAGGCCGTTTATTATCAACCCTTG
AAGTAGCCAGCAAGCGGAGTAATATGGTCGTTCTTTGCGGTGGTTTAGGACCAACTGAGGACGACCTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACGTGATTGATAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCGTCGGTCAGCTAGGGATAGAATCGGGCTGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(258-392)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

100

100

1
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus mitis SK321

54.808

100

0.58
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus mutans UA159

55.474

100

0.58
  cinA Streptococcus mitis NCTC 12261

54.567

100

0.578
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

41.379

95.929

0.397