Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   P8P68_RS08450 Genome accession   NZ_CP121467
Coordinates   1727505..1728761 (+) Length   418 a.a.
NCBI ID   WP_000642673.1    Uniprot ID   K0ZWC8
Organism   Streptococcus sp. D7B5     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1722505..1733761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS08425 (P8P68_08425) ndk 1724172..1724591 (+) 420 WP_000438308.1 nucleoside-diphosphate kinase -
  P8P68_RS08430 (P8P68_08430) comM 1724726..1725349 (+) 624 WP_049520827.1 hypothetical protein Regulator
  P8P68_RS08435 (P8P68_08435) tsaE 1725433..1725876 (+) 444 WP_000556959.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  P8P68_RS08440 (P8P68_08440) - 1725866..1726387 (+) 522 WP_000455514.1 GNAT family N-acetyltransferase -
  P8P68_RS08445 (P8P68_08445) - 1726392..1727432 (+) 1041 WP_000592171.1 LCP family protein -
  P8P68_RS08450 (P8P68_08450) cinA 1727505..1728761 (+) 1257 WP_000642673.1 competence/damage-inducible protein A Machinery gene
  P8P68_RS08455 (P8P68_08455) recA 1728816..1729967 (+) 1152 WP_001085520.1 recombinase RecA Machinery gene
  P8P68_RS08460 (P8P68_08460) - 1730097..1730291 (+) 195 WP_000415527.1 PspC domain-containing protein -
  P8P68_RS08465 (P8P68_08465) - 1730423..1730977 (-) 555 WP_000060284.1 GNAT family N-acetyltransferase -
  P8P68_RS08470 (P8P68_08470) - 1731087..1732457 (+) 1371 WP_247923962.1 MATE family efflux transporter -
  P8P68_RS08475 (P8P68_08475) - 1732554..1733270 (+) 717 WP_000532894.1 YebC/PmpR family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45142.53 Da        Isoelectric Point: 4.9847

>NTDB_id=812256 P8P68_RS08450 WP_000642673.1 1727505..1728761(+) (cinA) [Streptococcus sp. D7B5]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKDLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVSQERADQALDILENQI
LSRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFLGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSGFTARKMAEQARIKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=812256 P8P68_RS08450 WP_000642673.1 1727505..1728761(+) (cinA) [Streptococcus sp. D7B5]
ATGAAAGCAGAAATTATTGCTGTAGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTCTACTTCCAAACAGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTTG
AGATTGCGAGTCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACCGAGGATGATTTGACCAAACAAACC
CTGGCAAAATTTTTGGGAAAAGATCTAGTGTTTGACCCTCAAGCGCAAGAGAAACTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGGGTGTCAGAAGTGGATGGCGTGACCTACGTGGTCCTCCCAGGACCACCTAGTGAATTGAAACCCATG
GTCTTAAATCAACTCTTACCCAAGTTAATGACTGGTACCAAGTTATACTCACGAGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTGACCATTTTGGCGGATTTGATTGACCATCAAACCGATCCGACCTTGGCGCCGTATGCCAAGACGGGAG
AAGTGACCTTGCGTTTGTCTACAAAAGCAGTTAGTCAAGAAAGGGCTGATCAAGCACTGGATATCTTAGAAAATCAAATC
TTGAGTCGCCAAACTTTCGAGGGAATTTCTCTACGAGACATCTGTTATGGATATGGGGAAGAAACCAGTCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCGACAT
TAGCAGACTTTTTGGGCGTCTCAGCAATCTTTAATGGCGGTTTTGTCACTTACAGCCTAGAAGAAAAGTCCAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTTGTTTCTGGGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGAT
CAAGACTCAGTCTGATTATGGAGTTAGTTTGACGGGTGTGGCAGGGCCAGATAGCCTAGAGGGGCATCCAGCTGGTACAG
TTTTTATTGGATTGGCACATGCAAAAGGGACAGAGGTGATCAAGGCCAATATTGCAGGACGGAGTCGAGCAGATGTTCGA
CATATTGCGGTCATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0ZWC8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.713

100

0.897
  cinA Streptococcus pneumoniae TIGR4

89.234

100

0.892
  cinA Streptococcus pneumoniae Rx1

89.234

100

0.892
  cinA Streptococcus pneumoniae R6

89.234

100

0.892
  cinA Streptococcus mitis NCTC 12261

88.995

100

0.89
  cinA Streptococcus pneumoniae D39

88.995

100

0.89
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452