Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   P7F77_RS08170 Genome accession   NZ_CP121204
Coordinates   1676867..1677178 (-) Length   103 a.a.
NCBI ID   WP_000472255.1    Uniprot ID   A0A0U1MLR1
Organism   Staphylococcus aureus strain SA0907     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1677813..1678985 1676867..1677178 flank 635


Gene organization within MGE regions


Location: 1676867..1678985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7F77_RS08170 (P7F77_08175) comGC 1676867..1677178 (-) 312 WP_000472255.1 competence type IV pilus major pilin ComGC Machinery gene
  P7F77_RS08175 (P7F77_08180) - 1677192..1677710 (-) 519 Protein_1607 type II secretion system F family protein -
  P7F77_RS08180 (P7F77_08185) - 1677813..1678985 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -

Sequence

Protein


Download         Length: 103 a.a.        Molecular weight: 11301.33 Da        Isoelectric Point: 8.5268

>NTDB_id=811046 P7F77_RS08170 WP_000472255.1 1676867..1677178(-) (comGC) [Staphylococcus aureus strain SA0907]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGESITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=811046 P7F77_RS08170 WP_000472255.1 1676867..1677178(-) (comGC) [Staphylococcus aureus strain SA0907]
ATGTTTAAATTTCTAAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGTCAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1MLR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

99.029

100

0.99
  comGC Staphylococcus aureus MW2

99.029

100

0.99
  comGC/cglC Streptococcus mitis SK321

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456
  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427
  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408
  comYC Streptococcus suis isolate S10

50

75.728

0.379
  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369
  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369