Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   P1Y72_RS06785 Genome accession   NZ_CP119599
Coordinates   1403754..1404080 (+) Length   108 a.a.
NCBI ID   WP_032465607.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1133     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1398754..1409080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1Y72_RS06770 (P1Y72_06770) - 1401386..1401751 (+) 366 WP_002986560.1 DUF1033 family protein -
  P1Y72_RS06775 (P1Y72_06775) comYA 1401844..1402782 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  P1Y72_RS06780 (P1Y72_06780) comYB 1402718..1403752 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  P1Y72_RS06785 (P1Y72_06785) comYC 1403754..1404080 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  P1Y72_RS06790 (P1Y72_06790) comGD 1404055..1404483 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  P1Y72_RS06795 (P1Y72_06795) comGE 1404440..1404724 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  P1Y72_RS06800 (P1Y72_06800) comYF 1404717..1405151 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  P1Y72_RS06805 (P1Y72_06805) comGG 1405135..1405461 (+) 327 WP_136274078.1 competence type IV pilus minor pilin ComGG -
  P1Y72_RS06810 (P1Y72_06810) comYH 1405559..1406512 (+) 954 WP_136274080.1 class I SAM-dependent methyltransferase Machinery gene
  P1Y72_RS06815 (P1Y72_06815) - 1406571..1407767 (+) 1197 WP_023612537.1 acetate kinase -
  P1Y72_RS06820 (P1Y72_06820) - 1407954..1408262 (+) 309 WP_010921804.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12375.38 Da        Isoelectric Point: 10.0732

>NTDB_id=800066 P1Y72_RS06785 WP_032465607.1 1403754..1404080(+) (comYC) [Streptococcus pyogenes strain 1133]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYNKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=800066 P1Y72_RS06785 WP_032465607.1 1403754..1404080(+) (comYC) [Streptococcus pyogenes strain 1133]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATAACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444